Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
Location | 27668..28326 | Replicon | plasmid pAba7847b |
Accession | NZ_CP023033 | ||
Organism | Acinetobacter baumannii strain 7847 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | Aba7847_RS19495 | Protein ID | WP_000312250.1 |
Coordinates | 27668..28027 (+) | Length | 120 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | Aba7847_RS19500 | Protein ID | WP_001096429.1 |
Coordinates | 28027..28326 (+) | Length | 100 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
Aba7847_RS19460 | 23189..23503 | - | 315 | WP_000708714.1 | hypothetical protein | - |
Aba7847_RS19470 | 24559..25317 | - | 759 | WP_001053127.1 | hypothetical protein | - |
Aba7847_RS19475 | 25384..25767 | - | 384 | WP_000654348.1 | hypothetical protein | - |
Aba7847_RS19480 | 25905..26603 | - | 699 | WP_000873188.1 | hypothetical protein | - |
Aba7847_RS19485 | 26670..26852 | - | 183 | WP_000373385.1 | hypothetical protein | - |
Aba7847_RS19490 | 26901..27467 | - | 567 | WP_000710385.1 | hypothetical protein | - |
Aba7847_RS19495 | 27668..28027 | + | 360 | WP_000312250.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
Aba7847_RS19500 | 28027..28326 | + | 300 | WP_001096429.1 | helix-turn-helix transcriptional regulator | Antitoxin |
Aba7847_RS19510 | 28864..29400 | - | 537 | WP_000731978.1 | hypothetical protein | - |
Aba7847_RS19515 | 29450..30004 | - | 555 | WP_000790084.1 | hypothetical protein | - |
Aba7847_RS19520 | 30024..30242 | - | 219 | WP_001043201.1 | hypothetical protein | - |
Aba7847_RS19525 | 30282..30911 | - | 630 | WP_000701003.1 | hypothetical protein | - |
Aba7847_RS19530 | 30928..31107 | - | 180 | WP_000387630.1 | hypothetical protein | - |
Aba7847_RS19535 | 31083..31655 | - | 573 | WP_000443897.1 | hypothetical protein | - |
Aba7847_RS19540 | 31660..31917 | - | 258 | WP_000834290.1 | hypothetical protein | - |
Aba7847_RS19545 | 32022..33302 | - | 1281 | WP_063558595.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..80546 | 80546 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 120 a.a. Molecular weight: 13751.62 Da Isoelectric Point: 4.8212
>T80352 WP_000312250.1 NZ_CP023033:27668-28027 [Acinetobacter baumannii]
MAWDVETTELFDSWLAEQDENAQDKILASLLVLSELGPNLGRPHVDTIKESKYPNMKEIRVQVKGHPIRGFFAFDPERKA
IVLCAGDKKGLNEKAFYKEMIKIADEQYEQYLRDNYGDK
MAWDVETTELFDSWLAEQDENAQDKILASLLVLSELGPNLGRPHVDTIKESKYPNMKEIRVQVKGHPIRGFFAFDPERKA
IVLCAGDKKGLNEKAFYKEMIKIADEQYEQYLRDNYGDK
Download Length: 360 bp
>T80352 NZ_CP023033:27668-28027 [Acinetobacter baumannii]
ATGGCTTGGGATGTAGAAACAACAGAACTTTTTGATTCTTGGTTGGCAGAACAAGATGAAAATGCTCAAGATAAAATCTT
AGCGTCTTTGCTTGTTTTGTCAGAACTGGGGCCAAATCTAGGCCGGCCTCATGTTGATACTATTAAAGAATCAAAATATC
CGAACATGAAAGAGATACGTGTGCAAGTTAAAGGTCATCCGATCCGTGGTTTCTTTGCATTTGATCCAGAACGTAAAGCC
ATTGTTTTGTGTGCTGGAGATAAGAAAGGGCTAAATGAAAAAGCCTTTTATAAAGAAATGATCAAGATTGCAGATGAACA
ATATGAGCAATATTTACGTGATAATTACGGAGATAAATAA
ATGGCTTGGGATGTAGAAACAACAGAACTTTTTGATTCTTGGTTGGCAGAACAAGATGAAAATGCTCAAGATAAAATCTT
AGCGTCTTTGCTTGTTTTGTCAGAACTGGGGCCAAATCTAGGCCGGCCTCATGTTGATACTATTAAAGAATCAAAATATC
CGAACATGAAAGAGATACGTGTGCAAGTTAAAGGTCATCCGATCCGTGGTTTCTTTGCATTTGATCCAGAACGTAAAGCC
ATTGTTTTGTGTGCTGGAGATAAGAAAGGGCTAAATGAAAAAGCCTTTTATAAAGAAATGATCAAGATTGCAGATGAACA
ATATGAGCAATATTTACGTGATAATTACGGAGATAAATAA
Antitoxin
Download Length: 100 a.a. Molecular weight: 11012.93 Da Isoelectric Point: 10.4856
>AT80352 WP_001096429.1 NZ_CP023033:28027-28326 [Acinetobacter baumannii]
MAKLNDIISKRSPESQQRIKKMANQMLLDINLSNLREELKISQAEIAKNLGVSQAAISKREKLGKDLKISSLKEYVEAMG
GKVRLDVELPNGKHVAISI
MAKLNDIISKRSPESQQRIKKMANQMLLDINLSNLREELKISQAEIAKNLGVSQAAISKREKLGKDLKISSLKEYVEAMG
GKVRLDVELPNGKHVAISI
Download Length: 300 bp
>AT80352 NZ_CP023033:28027-28326 [Acinetobacter baumannii]
ATGGCTAAATTAAACGATATAATTTCAAAACGCTCACCTGAAAGCCAACAACGCATCAAGAAAATGGCAAATCAAATGCT
ATTGGATATTAACCTATCGAACCTACGGGAAGAGTTAAAAATATCTCAAGCTGAAATTGCAAAAAATCTAGGTGTAAGCC
AAGCTGCTATTTCAAAACGTGAAAAATTAGGTAAAGATCTTAAGATTTCATCATTAAAAGAATATGTTGAAGCTATGGGT
GGCAAAGTAAGGTTAGATGTTGAGTTACCTAACGGAAAGCATGTTGCTATATCTATTTAA
ATGGCTAAATTAAACGATATAATTTCAAAACGCTCACCTGAAAGCCAACAACGCATCAAGAAAATGGCAAATCAAATGCT
ATTGGATATTAACCTATCGAACCTACGGGAAGAGTTAAAAATATCTCAAGCTGAAATTGCAAAAAATCTAGGTGTAAGCC
AAGCTGCTATTTCAAAACGTGAAAAATTAGGTAAAGATCTTAAGATTTCATCATTAAAAGAATATGTTGAAGCTATGGGT
GGCAAAGTAAGGTTAGATGTTGAGTTACCTAACGGAAAGCATGTTGCTATATCTATTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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