80125

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2490117..2490301 Replicon chromosome
Accession NZ_CP022910
Organism Staphylococcus aureus strain 164

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag CGP88_RS13165 Protein ID WP_000482650.1
Coordinates 2490194..2490301 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2490117..2490177 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP88_RS13140 2485647..2485814 - 168 WP_001790576.1 hypothetical protein -
CGP88_RS13150 2486045..2487778 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
CGP88_RS13155 2487803..2489566 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2490117..2490177 + 61 - - Antitoxin
CGP88_RS13165 2490194..2490301 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
CGP88_RS13170 2490435..2490821 - 387 WP_000779358.1 flippase GtxA -
CGP88_RS13175 2491089..2492231 + 1143 WP_001176863.1 glycerate kinase -
CGP88_RS13180 2492291..2492950 + 660 WP_000831298.1 membrane protein -
CGP88_RS13185 2493132..2494343 + 1212 WP_001192076.1 multidrug effflux MFS transporter -
CGP88_RS13190 2494466..2494939 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T80125 WP_000482650.1 NZ_CP022910:c2490301-2490194 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T80125 NZ_CP022910:c2490301-2490194 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT80125 NZ_CP022910:2490117-2490177 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References