Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1864092..1864274 Replicon chromosome
Accession NZ_CP022910
Organism Staphylococcus aureus strain 164

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CGP88_RS09465 Protein ID WP_001801861.1
Coordinates 1864092..1864187 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1864215..1864274 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP88_RS09415 1859752..1860378 + 627 WP_000669046.1 hypothetical protein -
CGP88_RS09420 1860419..1860763 + 345 WP_000627551.1 DUF3969 family protein -
CGP88_RS09425 1860861..1861412 + 552 WP_000414205.1 hypothetical protein -
CGP88_RS09430 1861630..1862271 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
CGP88_RS09435 1862385..1862570 - 186 WP_000809857.1 hypothetical protein -
CGP88_RS09440 1862572..1862748 - 177 WP_000375476.1 hypothetical protein -
CGP88_RS09445 1862759..1863142 - 384 WP_000070811.1 hypothetical protein -
CGP88_RS09455 1863746..1863889 - 144 WP_001549059.1 transposase -
CGP88_RS09465 1864092..1864187 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1864215..1864274 - 60 - - Antitoxin
CGP88_RS09470 1864310..1864411 + 102 WP_001791893.1 hypothetical protein -
CGP88_RS09475 1864389..1864565 - 177 Protein_1780 transposase -
CGP88_RS09480 1864759..1865136 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA 1838066..1897365 59299


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T80112 WP_001801861.1 NZ_CP022910:1864092-1864187 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T80112 NZ_CP022910:1864092-1864187 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT80112 NZ_CP022910:c1864274-1864215 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References