Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2299973..2300236 Replicon chromosome
Accession NZ_CP022908
Organism Staphylococcus aureus strain 545

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CGQ00_RS12255 Protein ID WP_001802298.1
Coordinates 2300132..2300236 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2299973..2300137 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGQ00_RS12235 2296222..2296887 - 666 WP_001024094.1 SDR family oxidoreductase -
CGQ00_RS12240 2297039..2297359 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CGQ00_RS12245 2297361..2298341 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
CGQ00_RS12250 2298607..2299698 + 1092 WP_115276669.1 transcriptional regulator -
- 2299973..2300137 + 165 - - Antitoxin
CGQ00_RS12255 2300132..2300236 - 105 WP_001802298.1 hypothetical protein Toxin
CGQ00_RS15790 2300397..2300880 - 484 Protein_2262 recombinase family protein -
CGQ00_RS12265 2300923..2302059 - 1137 WP_115276670.1 SAP domain-containing protein -
CGQ00_RS12270 2302347..2302439 + 93 WP_001790138.1 hypothetical protein -
CGQ00_RS12275 2303144..2304001 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
CGQ00_RS12280 2304069..2304851 - 783 WP_000908177.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T80105 WP_001802298.1 NZ_CP022908:c2300236-2300132 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T80105 NZ_CP022908:c2300236-2300132 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT80105 NZ_CP022908:2299973-2300137 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References