80087

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2549573..2549757 Replicon chromosome
Accession NZ_CP022906
Organism Staphylococcus aureus strain 546

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag CGP99_RS13530 Protein ID WP_000482650.1
Coordinates 2549650..2549757 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2549573..2549633 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP99_RS13505 2545103..2545270 - 168 WP_001790576.1 hypothetical protein -
CGP99_RS13515 2545501..2547234 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
CGP99_RS13520 2547259..2549022 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2549573..2549633 + 61 - - Antitoxin
CGP99_RS13530 2549650..2549757 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
CGP99_RS13535 2549891..2550277 - 387 WP_000779358.1 flippase GtxA -
CGP99_RS13540 2550545..2551687 + 1143 WP_001176863.1 glycerate kinase -
CGP99_RS13545 2551747..2552406 + 660 WP_000831298.1 membrane protein -
CGP99_RS13550 2552588..2553799 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
CGP99_RS13555 2553922..2554395 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T80087 WP_000482650.1 NZ_CP022906:c2549757-2549650 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T80087 NZ_CP022906:c2549757-2549650 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT80087 NZ_CP022906:2549573-2549633 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References