80085

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2257422..2257685 Replicon chromosome
Accession NZ_CP022906
Organism Staphylococcus aureus strain 546

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CGP99_RS11935 Protein ID WP_001802298.1
Coordinates 2257581..2257685 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2257422..2257586 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP99_RS11915 2253671..2254336 - 666 WP_001024094.1 SDR family oxidoreductase -
CGP99_RS11920 2254488..2254808 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CGP99_RS11925 2254810..2255790 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
CGP99_RS11930 2256056..2257147 + 1092 WP_115276669.1 transcriptional regulator -
- 2257422..2257586 + 165 - - Antitoxin
CGP99_RS11935 2257581..2257685 - 105 WP_001802298.1 hypothetical protein Toxin
CGP99_RS15475 2257846..2258329 - 484 Protein_2197 recombinase family protein -
CGP99_RS11945 2258372..2259508 - 1137 WP_115276670.1 SAP domain-containing protein -
CGP99_RS11950 2259796..2259888 + 93 WP_001790138.1 hypothetical protein -
CGP99_RS11955 2260593..2261450 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
CGP99_RS11960 2261518..2262300 - 783 WP_000908177.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T80085 WP_001802298.1 NZ_CP022906:c2257685-2257581 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T80085 NZ_CP022906:c2257685-2257581 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT80085 NZ_CP022906:2257422-2257586 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References