Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2577597..2577781 Replicon chromosome
Accession NZ_CP022905
Organism Staphylococcus aureus strain 628

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag CGQ03_RS13595 Protein ID WP_000482652.1
Coordinates 2577674..2577781 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2577597..2577657 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGQ03_RS13570 2573052..2573219 - 168 Protein_2505 hypothetical protein -
CGQ03_RS13580 2573450..2575183 - 1734 WP_000486483.1 ABC transporter ATP-binding protein/permease -
CGQ03_RS13585 2575208..2576971 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 2577597..2577657 + 61 - - Antitoxin
CGQ03_RS13595 2577674..2577781 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
CGQ03_RS13600 2577915..2578301 - 387 WP_000779360.1 flippase GtxA -
CGQ03_RS13605 2578569..2579711 + 1143 WP_001176863.1 glycerate kinase -
CGQ03_RS13610 2579771..2580430 + 660 WP_000831302.1 hypothetical protein -
CGQ03_RS13615 2580612..2581823 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
CGQ03_RS13620 2581946..2582419 - 474 WP_015445934.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T80070 WP_000482652.1 NZ_CP022905:c2577781-2577674 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T80070 NZ_CP022905:c2577781-2577674 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT80070 NZ_CP022905:2577597-2577657 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References