Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 274687..274871 Replicon chromosome
Accession NZ_CP022904
Organism Staphylococcus aureus strain 629

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag CGQ02_RS01310 Protein ID WP_000482652.1
Coordinates 274687..274794 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 274811..274871 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGQ02_RS01285 270049..270522 + 474 WP_015445934.1 GyrI-like domain-containing protein -
CGQ02_RS01290 270645..271856 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
CGQ02_RS01295 272038..272697 - 660 WP_000831302.1 hypothetical protein -
CGQ02_RS01300 272757..273899 - 1143 WP_001176863.1 glycerate kinase -
CGQ02_RS01305 274167..274553 + 387 WP_000779360.1 flippase GtxA -
CGQ02_RS01310 274687..274794 + 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
- 274811..274871 - 61 - - Antitoxin
CGQ02_RS01320 275497..277260 + 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
CGQ02_RS01325 277285..279018 + 1734 WP_000486483.1 ABC transporter ATP-binding protein/permease -
CGQ02_RS01335 279249..279416 + 168 Protein_242 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T80040 WP_000482652.1 NZ_CP022904:274687-274794 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T80040 NZ_CP022904:274687-274794 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT80040 NZ_CP022904:c274871-274811 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References