80025

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 558451..558713 Replicon chromosome
Accession NZ_CP022903
Organism Staphylococcus aureus strain 187

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CGQ01_RS02865 Protein ID WP_001802298.1
Coordinates 558451..558555 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 558550..558713 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGQ01_RS02840 555248..556030 + 783 WP_000908182.1 ABC transporter ATP-binding protein -
CGQ01_RS02845 556098..556955 + 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
CGQ01_RS02855 557613..557771 - 159 WP_001792784.1 hypothetical protein -
CGQ01_RS02865 558451..558555 + 105 WP_001802298.1 hypothetical protein Toxin
- 558550..558713 - 164 - - Antitoxin
CGQ01_RS02870 558988..560079 - 1092 WP_000495669.1 hypothetical protein -
CGQ01_RS02875 560345..561322 - 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
CGQ01_RS02880 561324..561644 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CGQ01_RS02885 561796..562461 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T80025 WP_001802298.1 NZ_CP022903:558451-558555 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T80025 NZ_CP022903:558451-558555 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT80025 NZ_CP022903:c558713-558550 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References