80022

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 273355..273539 Replicon chromosome
Accession NZ_CP022903
Organism Staphylococcus aureus strain 187

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag CGQ01_RS01300 Protein ID WP_000482652.1
Coordinates 273355..273462 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 273479..273539 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGQ01_RS01275 268717..269190 + 474 WP_015445934.1 GyrI-like domain-containing protein -
CGQ01_RS01280 269313..270524 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
CGQ01_RS01285 270706..271365 - 660 WP_000831302.1 hypothetical protein -
CGQ01_RS01290 271425..272567 - 1143 WP_001176863.1 glycerate kinase -
CGQ01_RS01295 272835..273221 + 387 WP_000779360.1 flippase GtxA -
CGQ01_RS01300 273355..273462 + 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
- 273479..273539 - 61 - - Antitoxin
CGQ01_RS01310 274165..275928 + 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
CGQ01_RS01315 275953..277686 + 1734 WP_000486483.1 ABC transporter ATP-binding protein/permease -
CGQ01_RS01325 277917..278084 + 168 Protein_240 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T80022 WP_000482652.1 NZ_CP022903:273355-273462 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T80022 NZ_CP022903:273355-273462 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT80022 NZ_CP022903:c273539-273479 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References