Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprG-sprF/- |
Location | 2257415..2257678 | Replicon | chromosome |
Accession | NZ_CP022902 | ||
Organism | Staphylococcus aureus strain 165 |
Toxin (Protein)
Gene name | SprG3 | Uniprot ID | Q2FWA7 |
Locus tag | CGP98_RS11935 | Protein ID | WP_001802298.1 |
Coordinates | 2257574..2257678 (-) | Length | 35 a.a. |
Antitoxin (RNA)
Gene name | SprF4 | ||
Locus tag | - | ||
Coordinates | 2257415..2257579 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CGP98_RS11915 | 2253664..2254329 | - | 666 | WP_001024094.1 | SDR family oxidoreductase | - |
CGP98_RS11920 | 2254481..2254801 | + | 321 | WP_000003759.1 | Zn(II)-responsive metalloregulatory transcriptional repressor CzrA | - |
CGP98_RS11925 | 2254803..2255783 | + | 981 | WP_000019744.1 | CDF family zinc efflux transporter CzrB | - |
CGP98_RS11930 | 2256049..2257140 | + | 1092 | WP_115276669.1 | transcriptional regulator | - |
- | 2257415..2257579 | + | 165 | - | - | Antitoxin |
CGP98_RS11935 | 2257574..2257678 | - | 105 | WP_001802298.1 | hypothetical protein | Toxin |
CGP98_RS15330 | 2257839..2258322 | - | 484 | Protein_2196 | recombinase family protein | - |
CGP98_RS11945 | 2258365..2259501 | - | 1137 | WP_115276670.1 | SAP domain-containing protein | - |
CGP98_RS11950 | 2259789..2259881 | + | 93 | WP_001790138.1 | hypothetical protein | - |
CGP98_RS11955 | 2260586..2261443 | - | 858 | WP_000370924.1 | Cof-type HAD-IIB family hydrolase | - |
CGP98_RS11960 | 2261511..2262293 | - | 783 | WP_000908177.1 | ABC transporter ATP-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 35 a.a. Molecular weight: 3906.77 Da Isoelectric Point: 5.5724
>T80016 WP_001802298.1 NZ_CP022902:c2257678-2257574 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
Download Length: 105 bp
>T80016 NZ_CP022902:c2257678-2257574 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA
Antitoxin
Download Length: 165 bp
>AT80016 NZ_CP022902:2257415-2257579 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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