Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2508887..2509071 Replicon chromosome
Accession NZ_CP022901
Organism Staphylococcus aureus strain 466

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag CGP97_RS12925 Protein ID WP_000482647.1
Coordinates 2508964..2509071 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2508887..2508947 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP97_RS12900 2504397..2504564 - 168 Protein_2395 hypothetical protein -
CGP97_RS12910 2504795..2506528 - 1734 WP_115283889.1 ABC transporter ATP-binding protein/permease -
CGP97_RS12915 2506553..2508316 - 1764 WP_001064829.1 ABC transporter ATP-binding protein/permease -
- 2508887..2508947 + 61 - - Antitoxin
CGP97_RS12925 2508964..2509071 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
CGP97_RS12930 2509205..2509591 - 387 WP_000779351.1 flippase GtxA -
CGP97_RS12935 2509859..2511001 + 1143 WP_001176855.1 glycerate kinase -
CGP97_RS12940 2511061..2511720 + 660 WP_115283890.1 hypothetical protein -
CGP97_RS12945 2511902..2513113 + 1212 WP_001191919.1 multidrug effflux MFS transporter -
CGP97_RS12950 2513236..2513709 - 474 WP_000456496.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T80002 WP_000482647.1 NZ_CP022901:c2509071-2508964 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T80002 NZ_CP022901:c2509071-2508964 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT80002 NZ_CP022901:2508887-2508947 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References