Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2219443..2219659 Replicon chromosome
Accession NZ_CP022901
Organism Staphylococcus aureus strain 466

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag CGP97_RS11345 Protein ID WP_073392962.1
Coordinates 2219555..2219659 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2219443..2219498 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP97_RS11325 2214536..2214856 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CGP97_RS11330 2214858..2215838 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
CGP97_RS11335 2216104..2217195 + 1092 WP_000495684.1 hypothetical protein -
CGP97_RS11340 2217483..2219129 + 1647 WP_000277709.1 IS1182-like element ISSau3 family transposase -
- 2219443..2219498 + 56 - - Antitoxin
CGP97_RS11345 2219555..2219659 - 105 WP_073392962.1 hypothetical protein Toxin
CGP97_RS11355 2220339..2220497 + 159 WP_001792784.1 hypothetical protein -
CGP97_RS11365 2221156..2222013 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
CGP97_RS11370 2222081..2222863 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2217483..2219129 1646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T79999 WP_073392962.1 NZ_CP022901:c2219659-2219555 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T79999 NZ_CP022901:c2219659-2219555 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT79999 NZ_CP022901:2219443-2219498 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References