Detailed information of TA system TA079967

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2219387..2219603
• Replicon: chromosome
• Accession: NZ_CP022899
• Organism: Staphylococcus aureus strain 143

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: CGP95_RS11345
• Protein ID: WP_073392962.1
• Coordinates: 2219499..2219603 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	2219387..2219442 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CGP95_RS11325	2214480..2214800	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
CGP95_RS11330	2214802..2215782	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
CGP95_RS11335	2216048..2217139	+	1092	WP_000495684.1	hypothetical protein	-
CGP95_RS11340	2217427..2219073	+	1647	WP_000277709.1	IS1182-like element ISSau3 family transposase	-
-	2219387..2219442	+	56	-	-	Antitoxin
CGP95_RS11345	2219499..2219603	-	105	WP_073392962.1	hypothetical protein	Toxin
CGP95_RS11355	2220283..2220441	+	159	WP_001792784.1	hypothetical protein	-
CGP95_RS11365	2221100..2221957	-	858	WP_000370937.1	Cof-type HAD-IIB family hydrolase	-
CGP95_RS11370	2222025..2222807	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2217427..2219073	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T79967 WP_073392962.1 NZ_CP022899:c2219603-2219499 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T79967 NZ_CP022899:c2219603-2219499 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT79967 NZ_CP022899:2219387-2219442 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin