Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2219387..2219603 Replicon chromosome
Accession NZ_CP022899
Organism Staphylococcus aureus strain 143

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag CGP95_RS11345 Protein ID WP_073392962.1
Coordinates 2219499..2219603 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2219387..2219442 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP95_RS11325 2214480..2214800 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CGP95_RS11330 2214802..2215782 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
CGP95_RS11335 2216048..2217139 + 1092 WP_000495684.1 hypothetical protein -
CGP95_RS11340 2217427..2219073 + 1647 WP_000277709.1 IS1182-like element ISSau3 family transposase -
- 2219387..2219442 + 56 - - Antitoxin
CGP95_RS11345 2219499..2219603 - 105 WP_073392962.1 hypothetical protein Toxin
CGP95_RS11355 2220283..2220441 + 159 WP_001792784.1 hypothetical protein -
CGP95_RS11365 2221100..2221957 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
CGP95_RS11370 2222025..2222807 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2217427..2219073 1646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T79967 WP_073392962.1 NZ_CP022899:c2219603-2219499 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T79967 NZ_CP022899:c2219603-2219499 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT79967 NZ_CP022899:2219387-2219442 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References