Detailed information of TA system TA079958

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1876938..1877118
• Replicon: chromosome
• Accession: NZ_CP022899
• Organism: Staphylococcus aureus strain 143

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: CGP95_RS09240
• Protein ID: WP_001801861.1
• Coordinates: 1876938..1877033 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1877061..1877118 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CGP95_RS09205	1872082..1872708	+	627	WP_000669038.1	hypothetical protein	-
CGP95_RS09210	1872749..1873093	+	345	WP_000627550.1	DUF3969 family protein	-
CGP95_RS09215	1873191..1873763	+	573	WP_000414222.1	hypothetical protein	-
CGP95_RS09220	1873912..1875279	-	1368	WP_001093574.1	FRG domain-containing protein	-
CGP95_RS09225	1875279..1875848	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
CGP95_RS09230	1876041..1876487	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
CGP95_RS09240	1876938..1877033	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1877061..1877118	-	58	-	-	Antitoxin
CGP95_RS09245	1877156..1877257	+	102	WP_001791232.1	hypothetical protein	-
CGP95_RS09250	1877432..1877875	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
CGP95_RS09255	1877875..1878318	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
CGP95_RS09260	1878318..1878760	-	443	Protein_1749	DUF1433 domain-containing protein	-
CGP95_RS09265	1879285..1881705	+	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T79958 WP_001801861.1 NZ_CP022899:1876938-1877033 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T79958 NZ_CP022899:1876938-1877033 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT79958 NZ_CP022899:c1877118-1877061 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin