Detailed information of TA system TA079957

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1004437..1004686
• Replicon: chromosome
• Accession: NZ_CP022899
• Organism: Staphylococcus aureus strain 143

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: CGP95_RS04945
• Protein ID: WP_000623369.1
• Coordinates: 1004437..1004544 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	1004539..1004686 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CGP95_RS04920	1001110..1001679	-	570	WP_000287265.1	competence protein ComK	-
CGP95_RS04925	1001889..1002107	+	219	WP_000876825.1	IDEAL domain-containing protein	-
CGP95_RS04930	1002188..1003174	-	987	WP_000668820.1	lipoate--protein ligase	-
CGP95_RS04935	1003373..1003549	+	177	WP_000214898.1	YkvS family protein	-
CGP95_RS04940	1003564..1004166	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
CGP95_RS04945	1004437..1004544	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	1004539..1004686	-	148	-	-	Antitoxin
CGP95_RS04950	1005083..1005184	+	102	WP_001790623.1	hypothetical protein	-
CGP95_RS04955	1005194..1005466	+	273	WP_001794574.1	lactococcin 972 family bacteriocin	-
CGP95_RS04960	1005510..1007474	+	1965	WP_000870819.1	bacteriocin-associated integral membrane family protein	-
CGP95_RS04965	1007477..1007797	+	321	WP_000873929.1	YxeA family protein	-
CGP95_RS04970	1007794..1008435	+	642	WP_000571191.1	ABC transporter ATP-binding protein	-
CGP95_RS04975	1008523..1008813	-	291	WP_001791476.1	hypothetical protein	-
CGP95_RS04980	1009154..1009429	+	276	WP_115283836.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T79957 WP_000623369.1 NZ_CP022899:1004437-1004544 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T79957 NZ_CP022899:1004437-1004544 [Staphylococcus aureus]
GTGATATCTATTGCAAACGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 148 bp

>AT79957 NZ_CP022899:c1004686-1004539 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGGAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTTCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin