Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2214320..2214537 Replicon chromosome
Accession NZ_CP022898
Organism Staphylococcus aureus strain 422

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CGP94_RS11500 Protein ID WP_001802298.1
Coordinates 2214433..2214537 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2214320..2214375 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP94_RS11480 2210451..2211116 - 666 WP_001024091.1 SDR family oxidoreductase -
CGP94_RS11485 2211268..2211588 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CGP94_RS11490 2211590..2212570 + 981 WP_000019739.1 CDF family zinc efflux transporter CzrB -
CGP94_RS11495 2212836..2213927 + 1092 WP_047213685.1 hypothetical protein -
- 2214320..2214375 + 56 - - Antitoxin
CGP94_RS11500 2214433..2214537 - 105 WP_001802298.1 hypothetical protein Toxin
CGP94_RS14630 2214698..2215195 - 498 Protein_2116 recombinase family protein -
CGP94_RS11510 2215245..2216372 - 1128 WP_047213687.1 SAP domain-containing protein -
CGP94_RS11515 2217421..2218278 - 858 WP_000370936.1 Cof-type HAD-IIB family hydrolase -
CGP94_RS11520 2218346..2219128 - 783 WP_000908193.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T79951 WP_001802298.1 NZ_CP022898:c2214537-2214433 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T79951 NZ_CP022898:c2214537-2214433 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT79951 NZ_CP022898:2214320-2214375 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References