Detailed information of TA system TA079940

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2496559..2496743
• Replicon: chromosome
• Accession: NZ_CP022897
• Organism: Staphylococcus aureus strain 128

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: CGP93_RS13000
• Protein ID: WP_000482647.1
• Coordinates: 2496636..2496743 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2496559..2496619 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CGP93_RS12975	2492013..2492180	-	168	WP_031927726.1	hypothetical protein	-
CGP93_RS12985	2492411..2494144	-	1734	WP_000486497.1	ABC transporter ATP-binding protein/permease	-
CGP93_RS12990	2494169..2495932	-	1764	WP_115385584.1	ABC transporter ATP-binding protein/permease	-
-	2496559..2496619	+	61	-	-	Antitoxin
CGP93_RS13000	2496636..2496743	-	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
CGP93_RS13005	2496877..2497263	-	387	WP_000779353.1	flippase GtxA	-
CGP93_RS13010	2497531..2498673	+	1143	WP_001176870.1	glycerate kinase	-
CGP93_RS13015	2498733..2499392	+	660	WP_031927729.1	membrane protein	-
CGP93_RS13020	2499574..2500785	+	1212	WP_001191927.1	multidrug effflux MFS transporter	-
CGP93_RS13025	2500908..2501381	-	474	WP_000456493.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T79940 WP_000482647.1 NZ_CP022897:c2496743-2496636 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T79940 NZ_CP022897:c2496743-2496636 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT79940 NZ_CP022897:2496559-2496619 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin