Detailed information of TA system TA079916

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1872486..1872666
• Replicon: chromosome
• Accession: NZ_CP022896
• Organism: Staphylococcus aureus strain 277

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: CGP92_RS09245
• Protein ID: WP_001801861.1
• Coordinates: 1872486..1872581 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1872609..1872666 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CGP92_RS09210	1867630..1868256	+	627	WP_000669038.1	hypothetical protein	-
CGP92_RS09215	1868297..1868641	+	345	WP_000627550.1	DUF3969 family protein	-
CGP92_RS09220	1868739..1869311	+	573	WP_000414222.1	hypothetical protein	-
CGP92_RS09225	1869460..1870827	-	1368	WP_001093574.1	FRG domain-containing protein	-
CGP92_RS09230	1870827..1871396	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
CGP92_RS09235	1871589..1872035	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
CGP92_RS09245	1872486..1872581	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1872609..1872666	-	58	-	-	Antitoxin
CGP92_RS09250	1872704..1872805	+	102	WP_001791232.1	hypothetical protein	-
CGP92_RS09255	1872980..1873423	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
CGP92_RS09260	1873423..1873866	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
CGP92_RS09265	1873866..1874308	-	443	Protein_1750	DUF1433 domain-containing protein	-
CGP92_RS09270	1874833..1877253	+	2421	WP_115300166.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T79916 WP_001801861.1 NZ_CP022896:1872486-1872581 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T79916 NZ_CP022896:1872486-1872581 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT79916 NZ_CP022896:c1872666-1872609 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin