Detailed information of TA system TA079915

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 999005..999254
• Replicon: chromosome
• Accession: NZ_CP022896
• Organism: Staphylococcus aureus strain 277

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: CGP92_RS04945
• Protein ID: WP_000623369.1
• Coordinates: 999005..999112 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	999107..999254 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CGP92_RS04920	995692..996247	-	556	Protein_919	competence protein ComK	-
CGP92_RS04925	996457..996675	+	219	WP_000876825.1	IDEAL domain-containing protein	-
CGP92_RS04930	996756..997742	-	987	WP_000668820.1	lipoate--protein ligase	-
CGP92_RS04935	997941..998117	+	177	WP_000214898.1	YkvS family protein	-
CGP92_RS04940	998132..998734	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
CGP92_RS04945	999005..999112	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	999107..999254	-	148	-	-	Antitoxin
CGP92_RS04950	999651..999752	+	102	WP_001790623.1	hypothetical protein	-
CGP92_RS04955	999762..1000034	+	273	WP_001794574.1	lactococcin 972 family bacteriocin	-
CGP92_RS04960	1000078..1002042	+	1965	WP_000870819.1	bacteriocin-associated integral membrane family protein	-
CGP92_RS04965	1002045..1002365	+	321	WP_000873929.1	YxeA family protein	-
CGP92_RS04970	1002362..1003003	+	642	WP_000571191.1	ABC transporter ATP-binding protein	-
CGP92_RS04975	1003091..1003381	-	291	WP_001791476.1	hypothetical protein	-
CGP92_RS04980	1003722..1004009	+	288	WP_000410718.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T79915 WP_000623369.1 NZ_CP022896:999005-999112 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T79915 NZ_CP022896:999005-999112 [Staphylococcus aureus]
GTGATATCTATTGCAAACGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 148 bp

>AT79915 NZ_CP022896:c999254-999107 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGGAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTTCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin