Detailed information of TA system TA079900

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1873493..1873673
• Replicon: chromosome
• Accession: NZ_CP022895
• Organism: Staphylococcus aureus strain 85

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: CGP91_RS09250
• Protein ID: WP_001801861.1
• Coordinates: 1873493..1873588 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1873616..1873673 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CGP91_RS09215	1868637..1869263	+	627	WP_000669038.1	hypothetical protein	-
CGP91_RS09220	1869304..1869648	+	345	WP_000627550.1	DUF3969 family protein	-
CGP91_RS09225	1869746..1870318	+	573	WP_000414222.1	hypothetical protein	-
CGP91_RS09230	1870467..1871834	-	1368	WP_001093574.1	FRG domain-containing protein	-
CGP91_RS09235	1871834..1872403	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
CGP91_RS09240	1872596..1873042	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
CGP91_RS09250	1873493..1873588	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1873616..1873673	-	58	-	-	Antitoxin
CGP91_RS09255	1873711..1873812	+	102	WP_001791232.1	hypothetical protein	-
CGP91_RS09260	1873987..1874430	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
CGP91_RS09265	1874430..1874873	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
CGP91_RS09270	1874873..1875315	-	443	Protein_1751	DUF1433 domain-containing protein	-
CGP91_RS09275	1875840..1878260	+	2421	WP_115300166.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hysA / selk	1866078..1903435	37357

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T79900 WP_001801861.1 NZ_CP022895:1873493-1873588 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T79900 NZ_CP022895:1873493-1873588 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT79900 NZ_CP022895:c1873673-1873616 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin