Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2159053..2159316 Replicon chromosome
Accession NZ_CP022892
Organism Staphylococcus aureus strain 54

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CGP87_RS11210 Protein ID WP_001802298.1
Coordinates 2159212..2159316 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2159053..2159217 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP87_RS11190 2155236..2155901 - 666 WP_001024094.1 SDR family oxidoreductase -
CGP87_RS11195 2156053..2156373 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CGP87_RS11200 2156375..2157355 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
CGP87_RS11205 2157621..2158712 + 1092 WP_000495671.1 lytic regulatory protein -
- 2159053..2159217 + 165 - - Antitoxin
CGP87_RS11210 2159212..2159316 - 105 WP_001802298.1 hypothetical protein Toxin
CGP87_RS14400 2159477..2159960 - 484 Protein_2064 recombinase family protein -
CGP87_RS11220 2160003..2161139 - 1137 WP_000115564.1 SAP domain-containing protein -
CGP87_RS11225 2161428..2161520 + 93 WP_001790138.1 hypothetical protein -
CGP87_RS11230 2162225..2163082 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
CGP87_RS11235 2163150..2163932 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T79861 WP_001802298.1 NZ_CP022892:c2159316-2159212 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T79861 NZ_CP022892:c2159316-2159212 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT79861 NZ_CP022892:2159053-2159217 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References