Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1866523..1866705 Replicon chromosome
Accession NZ_CP022892
Organism Staphylococcus aureus strain 54

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CGP87_RS09475 Protein ID WP_001801861.1
Coordinates 1866523..1866618 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1866646..1866705 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP87_RS09425 1862183..1862809 + 627 WP_000669046.1 hypothetical protein -
CGP87_RS09430 1862850..1863194 + 345 WP_000627551.1 DUF3969 family protein -
CGP87_RS09435 1863292..1863843 + 552 WP_000414205.1 hypothetical protein -
CGP87_RS09440 1864061..1864702 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
CGP87_RS09445 1864816..1865001 - 186 WP_000809857.1 hypothetical protein -
CGP87_RS09450 1865003..1865179 - 177 WP_000375476.1 hypothetical protein -
CGP87_RS09455 1865190..1865573 - 384 WP_000070811.1 hypothetical protein -
CGP87_RS09465 1866177..1866320 - 144 WP_001549059.1 transposase -
CGP87_RS09475 1866523..1866618 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1866646..1866705 - 60 - - Antitoxin
CGP87_RS09480 1866741..1866842 + 102 WP_001791893.1 hypothetical protein -
CGP87_RS09485 1866820..1866996 - 177 Protein_1782 transposase -
CGP87_RS09490 1867190..1867567 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA 1840497..1899796 59299


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T79856 WP_001801861.1 NZ_CP022892:1866523-1866618 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T79856 NZ_CP022892:1866523-1866618 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT79856 NZ_CP022892:c1866705-1866646 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References