79648

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2419184..2419368 Replicon chromosome
Accession NZ_CP022720
Organism Staphylococcus aureus strain 135

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag CGP86_RS12510 Protein ID WP_000482647.1
Coordinates 2419261..2419368 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2419184..2419244 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP86_RS12485 2414638..2414805 - 168 WP_001792506.1 hypothetical protein -
CGP86_RS12495 2415036..2416769 - 1734 WP_000486496.1 ABC transporter ATP-binding protein/permease -
CGP86_RS12500 2416794..2418557 - 1764 WP_001064836.1 ABC transporter ATP-binding protein/permease -
- 2419184..2419244 + 61 - - Antitoxin
CGP86_RS12510 2419261..2419368 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
CGP86_RS12515 2419502..2419888 - 387 WP_000779360.1 flippase GtxA -
CGP86_RS12520 2420146..2421288 + 1143 WP_001176863.1 glycerate kinase -
CGP86_RS12525 2421348..2422007 + 660 WP_000831295.1 hypothetical protein -
CGP86_RS12530 2422189..2423400 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
CGP86_RS12535 2423523..2423996 - 474 WP_000456492.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T79648 WP_000482647.1 NZ_CP022720:c2419368-2419261 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T79648 NZ_CP022720:c2419368-2419261 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT79648 NZ_CP022720:2419184-2419244 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References