Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | SprA2-SprA2AS/- |
Location | 2501371..2501555 | Replicon | chromosome |
Accession | NZ_CP022717 | ||
Organism | Staphylococcus aureus strain 27 |
Toxin (Protein)
Gene name | SprA2 | Uniprot ID | A0A2P7CQJ7 |
Locus tag | CGP83_RS12975 | Protein ID | WP_000482647.1 |
Coordinates | 2501448..2501555 (-) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | SprA2AS | ||
Locus tag | - | ||
Coordinates | 2501371..2501431 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CGP83_RS12950 | 2496825..2496992 | - | 168 | WP_031927726.1 | hypothetical protein | - |
CGP83_RS12960 | 2497223..2498956 | - | 1734 | WP_000486497.1 | ABC transporter ATP-binding protein/permease | - |
CGP83_RS12965 | 2498981..2500744 | - | 1764 | WP_031927727.1 | ABC transporter ATP-binding protein/permease | - |
- | 2501371..2501431 | + | 61 | - | - | Antitoxin |
CGP83_RS12975 | 2501448..2501555 | - | 108 | WP_000482647.1 | type I toxin-antitoxin system Fst family toxin | Toxin |
CGP83_RS12980 | 2501689..2502075 | - | 387 | WP_000779353.1 | flippase GtxA | - |
CGP83_RS12985 | 2502343..2503485 | + | 1143 | WP_001176870.1 | glycerate kinase | - |
CGP83_RS12990 | 2503545..2504204 | + | 660 | WP_031927729.1 | membrane protein | - |
CGP83_RS12995 | 2504386..2505597 | + | 1212 | WP_115288437.1 | multidrug effflux MFS transporter | - |
CGP83_RS13000 | 2505720..2506193 | - | 474 | WP_000456493.1 | GyrI-like domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 4012.76 Da Isoelectric Point: 10.4935
>T79628 WP_000482647.1 NZ_CP022717:c2501555-2501448 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK
Download Length: 108 bp
>T79628 NZ_CP022717:c2501555-2501448 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA
Antitoxin
Download Length: 61 bp
>AT79628 NZ_CP022717:2501371-2501431 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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