79626

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2219009..2219226 Replicon chromosome
Accession NZ_CP022717
Organism Staphylococcus aureus strain 27

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CGP83_RS11475 Protein ID WP_001802298.1
Coordinates 2219122..2219226 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2219009..2219064 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP83_RS11455 2215143..2215808 - 666 WP_001024091.1 SDR family oxidoreductase -
CGP83_RS11460 2215960..2216280 + 321 WP_115288426.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CGP83_RS11465 2216282..2217259 + 978 WP_000019731.1 CDF family zinc efflux transporter CzrB -
CGP83_RS11470 2217525..2218616 + 1092 WP_047213685.1 hypothetical protein -
- 2219009..2219064 + 56 - - Antitoxin
CGP83_RS11475 2219122..2219226 - 105 WP_001802298.1 hypothetical protein Toxin
CGP83_RS14530 2219387..2219884 - 498 Protein_2113 recombinase family protein -
CGP83_RS11485 2219934..2221061 - 1128 WP_047213687.1 SAP domain-containing protein -
CGP83_RS11490 2222110..2222967 - 858 WP_000370936.1 Cof-type HAD-IIB family hydrolase -
CGP83_RS11495 2223035..2223817 - 783 WP_000908193.1 ABC transporter ATP-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T79626 WP_001802298.1 NZ_CP022717:c2219226-2219122 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T79626 NZ_CP022717:c2219226-2219122 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT79626 NZ_CP022717:2219009-2219064 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9


Antitoxin

Download structure file

References