Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2501313..2501497 Replicon chromosome
Accession NZ_CP022682
Organism Staphylococcus aureus strain 78

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag CGP84_RS12975 Protein ID WP_000482647.1
Coordinates 2501390..2501497 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2501313..2501373 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP84_RS12950 2496767..2496934 - 168 WP_031927726.1 hypothetical protein -
CGP84_RS12960 2497165..2498898 - 1734 WP_000486497.1 ABC transporter ATP-binding protein/permease -
CGP84_RS12965 2498923..2500686 - 1764 WP_031927727.1 ABC transporter ATP-binding protein/permease -
- 2501313..2501373 + 61 - - Antitoxin
CGP84_RS12975 2501390..2501497 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
CGP84_RS12980 2501631..2502017 - 387 WP_000779353.1 flippase GtxA -
CGP84_RS12985 2502285..2503427 + 1143 WP_001176870.1 glycerate kinase -
CGP84_RS12990 2503487..2504146 + 660 WP_031927729.1 membrane protein -
CGP84_RS12995 2504328..2505539 + 1212 WP_115288437.1 multidrug effflux MFS transporter -
CGP84_RS13000 2505662..2506135 - 474 WP_000456493.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T79517 WP_000482647.1 NZ_CP022682:c2501497-2501390 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T79517 NZ_CP022682:c2501497-2501390 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT79517 NZ_CP022682:2501313-2501373 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References