Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2218905..2219168 Replicon chromosome
Accession NZ_CP022682
Organism Staphylococcus aureus strain 78

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CGP84_RS11475 Protein ID WP_001802298.1
Coordinates 2219064..2219168 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2218905..2219069 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP84_RS11455 2215085..2215750 - 666 WP_001024091.1 SDR family oxidoreductase -
CGP84_RS11460 2215902..2216222 + 321 WP_115288426.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CGP84_RS11465 2216224..2217201 + 978 WP_000019731.1 CDF family zinc efflux transporter CzrB -
CGP84_RS11470 2217467..2218558 + 1092 WP_047213685.1 hypothetical protein -
- 2218905..2219069 + 165 - - Antitoxin
CGP84_RS11475 2219064..2219168 - 105 WP_001802298.1 hypothetical protein Toxin
CGP84_RS14740 2219329..2219826 - 498 Protein_2113 recombinase family protein -
CGP84_RS11485 2219876..2221003 - 1128 WP_047213687.1 SAP domain-containing protein -
CGP84_RS11490 2222052..2222909 - 858 WP_000370936.1 Cof-type HAD-IIB family hydrolase -
CGP84_RS11495 2222977..2223759 - 783 WP_000908193.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T79514 WP_001802298.1 NZ_CP022682:c2219168-2219064 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T79514 NZ_CP022682:c2219168-2219064 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT79514 NZ_CP022682:2218905-2219069 [Staphylococcus aureus]
GTAGTAAGTAGAAGTAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References