Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1805092..1805272 Replicon chromosome
Accession NZ_CP022607
Organism Staphylococcus aureus strain FORC_061

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag FORC61_RS08965 Protein ID WP_001801861.1
Coordinates 1805092..1805187 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1805215..1805272 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC61_RS08920 1800133..1800759 + 627 WP_000669021.1 hypothetical protein -
FORC61_RS08925 1800800..1801141 + 342 WP_000627547.1 DUF3969 family protein -
FORC61_RS08930 1801242..1801814 + 573 WP_000414206.1 hypothetical protein -
FORC61_RS08935 1802012..1802569 - 558 WP_000864139.1 ImmA/IrrE family metallo-endopeptidase -
FORC61_RS08945 1802940..1803116 - 177 WP_000375476.1 hypothetical protein -
FORC61_RS08950 1803127..1803510 - 384 WP_000070811.1 hypothetical protein -
FORC61_RS08955 1804195..1804641 - 447 WP_000747802.1 DUF1433 domain-containing protein -
FORC61_RS08965 1805092..1805187 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1805215..1805272 - 58 - - Antitoxin
FORC61_RS08970 1805310..1805411 + 102 WP_001791232.1 hypothetical protein -
FORC61_RS08975 1805389..1805571 - 183 Protein_1681 transposase -
FORC61_RS08980 1805759..1806133 - 375 WP_000695818.1 DUF1433 domain-containing protein -
FORC61_RS08985 1806155..1806502 - 348 WP_001566695.1 DUF1433 domain-containing protein -
FORC61_RS08990 1806712..1807155 - 444 WP_000742594.1 DUF1433 domain-containing protein -
FORC61_RS08995 1807803..1808921 - 1119 WP_000072558.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA / selk 1779277..1834167 54890


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T79405 WP_001801861.1 NZ_CP022607:1805092-1805187 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T79405 NZ_CP022607:1805092-1805187 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT79405 NZ_CP022607:c1805272-1805215 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References