Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2588025..2588209 Replicon chromosome
Accession NZ_CP022582
Organism Staphylococcus aureus strain FORC_062

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag FORC62_RS13660 Protein ID WP_000482652.1
Coordinates 2588102..2588209 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2588025..2588085 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC62_RS13635 2583480..2583647 - 168 Protein_2522 hypothetical protein -
FORC62_RS13645 2583878..2585611 - 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
FORC62_RS13650 2585636..2587399 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 2588025..2588085 + 61 - - Antitoxin
FORC62_RS13660 2588102..2588209 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
FORC62_RS13665 2588343..2588729 - 387 WP_000779360.1 flippase GtxA -
FORC62_RS13670 2588997..2590139 + 1143 WP_001176863.1 glycerate kinase -
FORC62_RS13675 2590199..2590858 + 660 WP_000831298.1 membrane protein -
FORC62_RS13680 2591040..2592251 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
FORC62_RS13685 2592374..2592847 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T79385 WP_000482652.1 NZ_CP022582:c2588209-2588102 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T79385 NZ_CP022582:c2588209-2588102 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT79385 NZ_CP022582:2588025-2588085 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References