Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 2004243..2004423 Replicon chromosome
Accession NZ_CP022582
Organism Staphylococcus aureus strain FORC_062

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag FORC62_RS10325 Protein ID WP_001801861.1
Coordinates 2004243..2004338 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2004366..2004423 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC62_RS10295 1999406..2000056 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
FORC62_RS10300 2000137..2001132 + 996 WP_000070642.1 DUF4352 domain-containing protein -
FORC62_RS10305 2001207..2001833 + 627 WP_000669024.1 hypothetical protein -
FORC62_RS10310 2001874..2002215 + 342 WP_000627540.1 DUF3969 family protein -
FORC62_RS10315 2002316..2002888 + 573 WP_000414216.1 hypothetical protein -
FORC62_RS10320 2003086..2004098 - 1013 Protein_1941 IS3 family transposase -
FORC62_RS10325 2004243..2004338 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 2004366..2004423 - 58 - - Antitoxin
FORC62_RS10330 2004461..2004562 + 102 WP_001792025.1 hypothetical protein -
FORC62_RS10335 2004540..2004701 - 162 Protein_1944 transposase -
FORC62_RS10340 2004692..2005186 - 495 Protein_1945 transposase -
FORC62_RS10345 2005638..2006867 - 1230 WP_000072626.1 restriction endonuclease subunit S -
FORC62_RS10350 2006860..2008416 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
FORC62_RS10355 2008580..2008714 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA / selk 1980225..2031255 51030


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T79377 WP_001801861.1 NZ_CP022582:2004243-2004338 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T79377 NZ_CP022582:2004243-2004338 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT79377 NZ_CP022582:c2004423-2004366 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References