Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 4926436..4927226 Replicon chromosome
Accession NZ_CP022562
Organism Pseudomonas monteilii strain B5

Toxin (Protein)


Gene name yhaV Uniprot ID A0A3G2HLC0
Locus tag CHR29_RS23230 Protein ID WP_016713503.1
Coordinates 4926759..4927226 (+) Length 156 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID A0A0P7D0H8
Locus tag CHR29_RS23225 Protein ID WP_016713504.1
Coordinates 4926436..4926762 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CHR29_RS23205 4921972..4923033 - 1062 WP_016713508.1 HlyD family secretion protein -
CHR29_RS23210 4923062..4924603 - 1542 WP_016713507.1 MFS transporter -
CHR29_RS23215 4924720..4925625 - 906 WP_016713506.1 LysR family transcriptional regulator -
CHR29_RS23220 4925896..4926342 + 447 WP_016713505.1 universal stress protein -
CHR29_RS23225 4926436..4926762 + 327 WP_016713504.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
CHR29_RS23230 4926759..4927226 + 468 WP_016713503.1 type II toxin-antitoxin system YhaV family toxin Toxin
CHR29_RS23235 4927272..4928132 - 861 WP_121757793.1 HlyD family secretion protein -
CHR29_RS23240 4928143..4928343 - 201 WP_009685040.1 DUF1656 domain-containing protein -
CHR29_RS23245 4928333..4930510 - 2178 WP_016713501.1 FUSC family protein -
CHR29_RS23250 4930507..4932036 - 1530 WP_016713500.1 efflux transporter outer membrane subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(17-152)

Antitoxin

PrlF antitoxin

(8-106)


Sequences

Toxin        


Download         Length: 156 a.a.        Molecular weight: 18037.56 Da        Isoelectric Point: 10.0504

>T79224 WP_016713503.1 NZ_CP022562:4926759-4927226 [Pseudomonas monteilii]
MSDASRKPLVIHGWTVIAHPLFLAKLEALSAQVQAQMHKDPTGYTRRNAYKRLAAIKRLAFDVIPQDPTKPEYRQGATLG
GDHKHWFRAKFFQQYRLFFRYHTPSRIIVLAWVNDESSKRAYESSDDAYKVFQKMLHTGHPPDDWEQLLREAAAE

Download         Length: 468 bp

>T79224 NZ_CP022562:4926759-4927226 [Pseudomonas monteilii]
ATGAGTGATGCGAGCAGGAAGCCTCTGGTTATTCATGGATGGACTGTAATTGCCCACCCGCTGTTCCTGGCCAAACTGGA
GGCACTCAGCGCTCAAGTGCAGGCTCAGATGCACAAGGACCCAACGGGTTACACGCGCAGAAATGCCTATAAAAGGCTGG
CGGCCATCAAGCGACTGGCCTTCGATGTAATCCCTCAAGACCCGACCAAACCTGAGTACCGGCAGGGGGCCACACTGGGT
GGTGACCACAAGCACTGGTTCAGGGCAAAGTTCTTCCAGCAGTACCGGTTGTTCTTCCGCTATCACACCCCCAGCAGGAT
CATTGTGCTGGCCTGGGTCAATGACGAGTCGAGCAAGCGGGCCTACGAAAGTAGCGACGATGCTTACAAGGTCTTTCAGA
AGATGCTGCATACCGGCCACCCGCCGGACGATTGGGAGCAGCTACTGCGAGAAGCTGCAGCCGAATGA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12007.46 Da        Isoelectric Point: 4.3118

>AT79224 WP_016713504.1 NZ_CP022562:4926436-4926762 [Pseudomonas monteilii]
MATTLDVESTLTDRYQTTVPETVRRALGLKKRDKIHYSIRPDGEVILTRAEATESDPVLGKFLDFLAHDIATNPQRLQVV
DADLIARLDKLVGDAEVDLDQSLSADDE

Download         Length: 327 bp

>AT79224 NZ_CP022562:4926436-4926762 [Pseudomonas monteilii]
ATGGCAACCACTCTCGACGTCGAGTCCACACTGACCGATCGCTATCAGACCACTGTTCCCGAAACAGTACGGCGCGCCTT
GGGCTTGAAAAAACGTGACAAGATCCATTACTCGATTCGCCCTGACGGTGAGGTGATACTCACCCGTGCAGAAGCAACCG
AGAGCGATCCAGTACTGGGCAAATTTCTGGATTTCCTGGCACACGATATCGCCACCAACCCTCAACGGCTGCAGGTTGTC
GATGCTGACCTCATCGCGCGTCTCGACAAGCTTGTCGGCGACGCAGAGGTCGACCTGGATCAATCTCTGTCGGCGGATGA
TGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2HLC0

Antitoxin

Source ID Structure
AlphaFold DB A0A0P7D0H8

References