Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 5084644..5085434 Replicon chromosome
Accession NZ_CP022561
Organism Pseudomonas putida strain B4

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag CHN49_RS23855 Protein ID WP_014859916.1
Coordinates 5084967..5085434 (+) Length 156 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag CHN49_RS23850 Protein ID WP_121784053.1
Coordinates 5084644..5084970 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CHN49_RS23830 5080159..5081220 - 1062 WP_003251732.1 HlyD family secretion protein -
CHN49_RS23835 5081249..5082790 - 1542 WP_121784052.1 MFS transporter -
CHN49_RS23840 5082926..5083831 - 906 WP_014859919.1 LysR family transcriptional regulator -
CHN49_RS23845 5084105..5084551 + 447 WP_014859918.1 universal stress protein -
CHN49_RS23850 5084644..5084970 + 327 WP_121784053.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
CHN49_RS23855 5084967..5085434 + 468 WP_014859916.1 type II toxin-antitoxin system YhaV family toxin Toxin
CHN49_RS23860 5085507..5086367 - 861 WP_014859915.1 HlyD family secretion protein -
CHN49_RS23865 5086378..5086578 - 201 WP_014859914.1 DUF1656 domain-containing protein -
CHN49_RS23870 5086568..5088745 - 2178 WP_003251716.1 FUSC family protein -
CHN49_RS23875 5088742..5090271 - 1530 WP_014859913.1 efflux transporter outer membrane subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(17-152)

Antitoxin

PrlF antitoxin

(8-106)


Sequences

Toxin        


Download         Length: 156 a.a.        Molecular weight: 17998.38 Da        Isoelectric Point: 9.7964

>T79221 WP_014859916.1 NZ_CP022561:5084967-5085434 [Pseudomonas putida]
MSDASRKPLVIHGWTVIAHPLFLAKLDALSAQVEAQRDKDPTGYTKRNTFKRLAAIRRLAFDVIPQDPTKPEYRQGATLG
GDHKHWFRAKFFQQYRLFFRYHTPSRIIVLAWVNDESSKRAYESNDDAYKVFQKMLHSGHPPDDWDQLLQEAAAD

Download         Length: 468 bp

>T79221 NZ_CP022561:5084967-5085434 [Pseudomonas putida]
ATGAGTGATGCGAGCAGGAAGCCTCTGGTTATTCATGGATGGACTGTAATTGCCCACCCGCTGTTCCTGGCCAAACTGGA
CGCGCTAAGCGCTCAAGTCGAGGCTCAACGGGACAAAGACCCAACGGGTTATACGAAAAGAAATACCTTTAAAAGGCTGG
CCGCCATCCGGCGGTTGGCGTTCGATGTAATCCCTCAAGACCCGACCAAACCCGAATACCGGCAAGGCGCAACACTTGGC
GGTGACCACAAGCACTGGTTCAGAGCAAAGTTCTTCCAGCAGTACCGGTTGTTCTTCCGCTACCACACCCCCAGCAGGAT
CATCGTGCTGGCCTGGGTCAATGACGAGTCGAGCAAGCGGGCCTATGAAAGTAACGACGATGCTTACAAGGTCTTTCAAA
AGATGTTGCATAGCGGCCACCCACCGGACGATTGGGACCAGTTGCTGCAAGAGGCTGCCGCAGATTGA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 11915.41 Da        Isoelectric Point: 4.3722

>AT79221 WP_121784053.1 NZ_CP022561:5084644-5084970 [Pseudomonas putida]
MAATFDVESTLTDRYQTTVPETVRRALGLKKRDKIHYSIRPDGGVILTRAEAPEDDPVLGKFLDFLAHDIATNPQRLQVV
DAGLIARLDKLVGDAEVDLDQPLSADDE

Download         Length: 327 bp

>AT79221 NZ_CP022561:5084644-5084970 [Pseudomonas putida]
ATGGCTGCCACCTTCGACGTCGAGTCCACGCTGACCGATCGCTATCAAACCACTGTTCCCGAAACGGTGCGGCGCGCCTT
GGGCTTGAAAAAACGTGACAAGATCCATTACTCGATTCGCCCCGACGGTGGGGTGATACTCACCCGCGCAGAGGCACCCG
AGGACGATCCGGTACTGGGCAAATTTCTGGATTTCCTGGCACACGATATCGCTACCAACCCTCAACGGCTGCAGGTTGTC
GATGCTGGCCTCATCGCGCGCCTCGACAAGCTTGTCGGCGACGCGGAGGTCGACCTGGATCAACCTCTGTCGGCGGACGA
TGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References