Detailed information of TA system TA079218

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 1830667..1831367
• Replicon: chromosome
• Accession: NZ_CP022561
• Organism: Pseudomonas putida strain B4

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: Q88F93
• Locus tag: CHN49_RS08675
• Protein ID: WP_010954960.1
• Coordinates: 1830667..1830963 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: I7AUJ7
• Locus tag: CHN49_RS08680
• Protein ID: WP_003254235.1
• Coordinates: 1830966..1831367 (+)
• Length: 134 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CHN49_RS08655	1826306..1827928	+	1623	WP_121783112.1	twin-arginine translocation signal domain-containing protein	-
CHN49_RS08660	1828050..1828526	+	477	WP_014859270.1	sigma-70 family RNA polymerase sigma factor	-
CHN49_RS08665	1828695..1829174	+	480	WP_012051716.1	hypothetical protein	-
CHN49_RS08670	1829247..1830572	+	1326	WP_121783113.1	MFS transporter	-
CHN49_RS08675	1830667..1830963	+	297	WP_010954960.1	type II toxin-antitoxin system MqsR family toxin	Toxin
CHN49_RS08680	1830966..1831367	+	402	WP_003254235.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
CHN49_RS08685	1831439..1833121	-	1683	WP_023389616.1	electron transfer flavoprotein-ubiquinone oxidoreductase	-
CHN49_RS08690	1833657..1834406	+	750	WP_003254232.1	electron transfer flavoprotein subunit beta/FixA family protein	-
CHN49_RS08695	1834408..1835349	+	942	WP_004573654.1	FAD-binding protein	-
CHN49_RS08700	1835425..1836246	+	822	WP_121783114.1	transporter substrate-binding domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (6-97)

Antitoxin

• Cro/C1-type helix-turn-helix domain (74-109)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11133.22 Da
• Isoelectric Point: 10.2271

>T79218 WP_010954960.1 NZ_CP022561:1830667-1830963 [Pseudomonas putida]
MEKRMPHCPLERVKALAAARRIRPTGAALKGAKALGMDFPGMLEVITSLKRTDFYKSMTSHIDHRVWQDVYRPLTAIGYV
YLKLSVVDDVLIVSFKEL

Nucleotide

• Length: 297 bp

>T79218 NZ_CP022561:1830667-1830963 [Pseudomonas putida]
ATGGAAAAGAGAATGCCTCATTGCCCGCTGGAGCGGGTAAAAGCCCTGGCTGCGGCAAGGCGAATCCGCCCTACGGGTGC
TGCATTGAAAGGCGCCAAGGCGCTGGGAATGGATTTTCCGGGCATGCTTGAGGTGATCACCAGCTTGAAGCGCACTGATT
TCTACAAGAGCATGACCAGCCATATTGACCACCGGGTTTGGCAGGATGTGTATCGCCCGCTTACAGCAATTGGGTACGTT
TATTTGAAATTGTCCGTGGTAGACGACGTGCTCATCGTGTCTTTCAAGGAGTTGTAA

Antitoxin

Protein

• Length: 134 a.a.
• Molecular weight: 14684.76 Da
• Isoelectric Point: 4.9531

>AT79218 WP_003254235.1 NZ_CP022561:1830966-1831367 [Pseudomonas putida]
MRCPICGGSELAPDIQGMPYSYKGEMTVIPEVSGDYCSACGECVLSHDEAMRVSHLMTAFERQVNANVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Nucleotide

• Length: 402 bp

>AT79218 NZ_CP022561:1830966-1831367 [Pseudomonas putida]
ATGAGATGTCCAATATGCGGCGGCTCGGAGCTTGCACCTGACATTCAGGGCATGCCCTATAGCTACAAAGGCGAGATGAC
AGTGATCCCTGAGGTAAGTGGCGATTACTGCTCCGCATGTGGTGAATGTGTACTGAGTCATGATGAAGCCATGCGCGTCA
GTCACTTGATGACGGCATTCGAGCGCCAGGTCAACGCAAATGTTGTGGATCCTTCCTTTATTGCCTCCATACGCAGAAAG
TTCGACCTCGACCAGCGTGAAGCGGGGGAAATTTTCGGTGGTGGGGTCAATGCGTTCTCCCGCTATGAAAACGGCAAGAC
CACACCGCCAGTGGCGTTGGTGAAACTGCTCAAGCTGCTGGATCGCCATCCAGAACTCTTTGAGGAAGTGCGTACTGCCT
GA

Structures

Toxin

• AlphaFold DB: Q88F93

Antitoxin

• AlphaFold DB: I7AUJ7