Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 3794473..3795173 Replicon chromosome
Accession NZ_CP022560
Organism Pseudomonas putida strain B1

Toxin (Protein)


Gene name mqsR Uniprot ID A0A8I0Z9R5
Locus tag CHR26_RS17945 Protein ID WP_060519866.1
Coordinates 3794473..3794769 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A8I0Z3K6
Locus tag CHR26_RS17950 Protein ID WP_024717924.1
Coordinates 3794772..3795173 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CHR26_RS17920 3789790..3790971 - 1182 WP_145913929.1 efflux RND transporter periplasmic adaptor subunit -
CHR26_RS17925 3791202..3791702 + 501 WP_095116961.1 sigma-70 family RNA polymerase sigma factor -
CHR26_RS17930 3791740..3792201 - 462 WP_023048064.1 azurin -
CHR26_RS17935 3792501..3792980 + 480 WP_023048065.1 hypothetical protein -
CHR26_RS17940 3793053..3794378 + 1326 WP_016488294.1 MFS transporter -
CHR26_RS17945 3794473..3794769 + 297 WP_060519866.1 type II toxin-antitoxin system MqsR family toxin Toxin
CHR26_RS17950 3794772..3795173 + 402 WP_024717924.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
CHR26_RS17955 3795244..3796926 - 1683 WP_080641073.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
CHR26_RS17965 3797460..3798209 + 750 WP_016488290.1 electron transfer flavoprotein subunit beta/FixA family protein -
CHR26_RS17970 3798210..3799139 + 930 WP_016488289.1 FAD-binding protein -
CHR26_RS17975 3799215..3800036 + 822 WP_023048067.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11175.10 Da        Isoelectric Point: 9.0375

>T79215 WP_060519866.1 NZ_CP022560:3794473-3794769 [Pseudomonas putida]
MEKRTPHCPLERVKVLAAARRISPTGAALRGARALGMDYPGMLEVISCLERTDFYKSMTSHMDHRVWQDVYRPLTAFGYV
YLKVSVVDDVLIVSFKEL

Download         Length: 297 bp

>T79215 NZ_CP022560:3794473-3794769 [Pseudomonas putida]
ATGGAAAAGAGAACGCCTCACTGTCCGTTGGAAAGGGTAAAAGTCTTGGCTGCTGCAAGGCGCATCAGCCCTACAGGCGC
TGCACTGAGAGGCGCCAGAGCCCTGGGAATGGATTATCCGGGCATGCTTGAAGTGATCTCCTGTTTGGAGCGTACTGATT
TCTACAAGAGCATGACCAGCCATATGGATCACCGCGTTTGGCAGGACGTCTATCGTCCGCTTACAGCATTTGGGTACGTT
TATCTGAAAGTGTCCGTGGTAGACGACGTGCTCATCGTGTCTTTCAAGGAGTTGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14516.57 Da        Isoelectric Point: 4.7550

>AT79215 WP_024717924.1 NZ_CP022560:3794772-3795173 [Pseudomonas putida]
MRCPVCGGAELAPDVQGMPYSYKGEATVIPDVSGDYCCACGECVLSHDEAMRVSNLMTAFERQVNAAVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT79215 NZ_CP022560:3794772-3795173 [Pseudomonas putida]
ATGAGATGTCCAGTATGCGGCGGTGCGGAGCTTGCACCTGATGTTCAGGGGATGCCCTATAGCTATAAAGGAGAGGCGAC
CGTCATCCCTGACGTAAGTGGCGATTACTGTTGCGCCTGTGGTGAATGTGTACTTAGCCACGATGAAGCCATGCGTGTCA
GTAACCTGATGACGGCATTCGAGCGTCAAGTCAACGCAGCTGTTGTGGATCCTTCCTTCATTGCTTCAATCCGCCGTAAG
TTCGACCTCGACCAGCGTGAAGCGGGGGAAATTTTCGGGGGTGGCGTCAACGCGTTCTCCCGTTATGAAAACGGCAAGAC
CACACCACCCGTGGCGTTGGTGAAACTGCTCAAGCTGCTGGATCGCCATCCAGAACTCTTCGAGGAAGTGCGTACTGCCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References