Detailed information of TA system TA079206

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-YefM
• Location: 1168131..1168648
• Replicon: chromosome
• Accession: NZ_CP022548
• Organism: Sphingorhabdus sp. YGSMI21

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: CHN51_RS05685
• Protein ID: WP_100093160.1
• Coordinates: 1168382..1168648 (+)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: CHN51_RS05680
• Protein ID: WP_100093159.1
• Coordinates: 1168131..1168385 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CHN51_RS05660	1164031..1164939	-	909	WP_100093155.1	prephenate/arogenate dehydrogenase family protein	-
CHN51_RS05665	1164939..1166039	-	1101	WP_100093156.1	histidinol-phosphate transaminase	-
CHN51_RS05670	1166155..1167279	+	1125	WP_100093157.1	homoserine O-acetyltransferase	-
CHN51_RS05675	1167404..1167994	+	591	WP_100093158.1	methionine biosynthesis protein MetW	-
CHN51_RS05680	1168131..1168385	+	255	WP_100093159.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
CHN51_RS05685	1168382..1168648	+	267	WP_100093160.1	Txe/YoeB family addiction module toxin	Toxin
CHN51_RS05690	1168982..1170283	-	1302	WP_100093161.1	MFS transporter	-
CHN51_RS05695	1170301..1171863	-	1563	WP_100093162.1	peptide chain release factor 3	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (2-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (5-73)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10710.17 Da
• Isoelectric Point: 9.9618

>T79206 WP_100093160.1 NZ_CP022548:1168382-1168648 [Sphingorhabdus sp. YGSMI21]
VNVLFSGKSWPEYRYFQEHDPKLSERIYSLIEECRRTPFRGTGKPEPLRGQLKGWWSRRINREHRLVYRVRGEGAEQVLE
IAQCRYHY

Nucleotide

• Length: 267 bp

>T79206 NZ_CP022548:1168382-1168648 [Sphingorhabdus sp. YGSMI21]
GTGAATGTATTATTCTCCGGGAAAAGTTGGCCGGAATATCGATATTTCCAGGAACATGATCCAAAGCTTTCCGAACGAAT
ATATTCGCTGATAGAGGAATGTCGCCGGACGCCTTTCCGCGGTACCGGCAAGCCAGAGCCATTGCGCGGCCAACTGAAAG
GCTGGTGGTCGCGGCGTATAAACCGCGAGCACCGCCTGGTCTATCGCGTCCGTGGCGAAGGGGCAGAGCAAGTGCTGGAA
ATAGCGCAATGCCGATATCATTATTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9501.98 Da
• Isoelectric Point: 4.8481

>AT79206 WP_100093159.1 NZ_CP022548:1168131-1168385 [Sphingorhabdus sp. YGSMI21]
MLMENFSKARANLKALMDRVVADKIPLKITRQNGEAVVMISESEWAGMEETIHLLSSPKNAERLLESIRQLDAGEGFEPE
LFKQ

Nucleotide

• Length: 255 bp

>AT79206 NZ_CP022548:1168131-1168385 [Sphingorhabdus sp. YGSMI21]
ATGTTGATGGAAAATTTCTCGAAGGCCCGCGCCAATCTCAAGGCGCTGATGGATCGCGTCGTGGCGGACAAGATTCCCCT
GAAAATTACCCGTCAAAATGGCGAGGCGGTGGTCATGATCTCGGAGAGTGAGTGGGCCGGTATGGAAGAAACTATCCATT
TACTGTCTTCACCAAAAAATGCCGAACGCTTGCTGGAGTCGATAAGGCAACTTGATGCCGGAGAGGGATTCGAGCCTGAG
CTTTTCAAGCAGTGA