Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 649861..650390 Replicon chromosome
Accession NZ_CP022544
Organism Bifidobacterium pseudolongum strain UMB-MBP-01

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag BPSOL_RS02775 Protein ID WP_095507582.1
Coordinates 649861..650124 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag BPSOL_RS02780 Protein ID WP_095507583.1
Coordinates 650130..650390 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BPSOL_RS02755 646411..646689 + 279 WP_157732248.1 hypothetical protein -
BPSOL_RS08540 646783..647709 - 927 WP_157732249.1 ImpB/MucB/SamB family protein -
BPSOL_RS02760 648099..648782 + 684 WP_095507580.1 pentapeptide repeat-containing protein -
BPSOL_RS02765 648840..649352 + 513 WP_095507581.1 DUF4065 domain-containing protein -
BPSOL_RS02770 649352..649864 + 513 WP_095508305.1 Fic family protein -
BPSOL_RS02775 649861..650124 - 264 WP_095507582.1 Txe/YoeB family addiction module toxin Toxin
BPSOL_RS02780 650130..650390 - 261 WP_095507583.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
BPSOL_RS02785 650517..650996 - 480 WP_095507584.1 GNAT family N-acetyltransferase -
BPSOL_RS02790 651043..651840 - 798 WP_095507585.1 DUF1295 domain-containing protein -
BPSOL_RS02795 652073..653482 + 1410 WP_095507293.1 IS481 family transposase -
BPSOL_RS02800 653645..654628 - 984 WP_095507586.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 642224..654628 12404


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10443.07 Da        Isoelectric Point: 9.7709

>T79204 WP_095507582.1 NZ_CP022544:c650124-649861 [Bifidobacterium pseudolongum]
MKLTWTADAWNDYLYWQSQDKKTLKRINLLIKDIMRNPFEGIGKPEPLQWDFAGAWSRRISEKHRIIYMPKADSIVVLSC
REHYKDS

Download         Length: 264 bp

>T79204 NZ_CP022544:c650124-649861 [Bifidobacterium pseudolongum]
ATGAAATTGACGTGGACAGCCGACGCGTGGAACGACTACCTCTACTGGCAGAGCCAAGACAAGAAGACACTCAAGCGCAT
CAATTTGCTTATCAAAGACATCATGCGCAATCCATTCGAAGGCATCGGCAAACCCGAGCCATTGCAATGGGATTTCGCTG
GAGCGTGGTCACGCCGCATCAGTGAGAAGCACCGCATCATCTACATGCCCAAAGCAGACAGCATTGTGGTCCTCTCCTGC
CGAGAGCACTACAAGGATTCCTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 10089.31 Da        Isoelectric Point: 4.4978

>AT79204 WP_095507583.1 NZ_CP022544:c650390-650130 [Bifidobacterium pseudolongum]
MRAITYSSFRNNLKENIRQIREDAEPLLVTNKDAEDNIIVMNQSDYDSLMETLRIYRNPVMYERIRRGMQQAADGDVAEH
SLLPED

Download         Length: 261 bp

>AT79204 NZ_CP022544:c650390-650130 [Bifidobacterium pseudolongum]
ATGCGCGCAATAACCTACAGTTCATTCCGCAATAACCTCAAAGAGAACATCAGGCAGATTCGCGAGGACGCGGAACCGCT
TCTCGTCACGAACAAAGACGCGGAAGACAACATCATCGTCATGAACCAATCCGATTACGACAGCCTTATGGAGACACTGC
GCATCTACCGCAATCCGGTGATGTACGAGCGCATCCGCCGTGGCATGCAGCAGGCCGCCGACGGAGATGTCGCCGAGCAC
AGCCTTCTGCCCGAGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References