Detailed information of TA system TA079143

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2626902..2627280
• Replicon: chromosome
• Accession: NZ_CP022488
• Organism: Enterococcus faecalis ARO1/DG

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: CG806_RS14260
• Protein ID: WP_002367503.1
• Coordinates: 2626902..2627090 (+)
• Length: 63 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2627046..2627280 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CG806_RS14235	2622197..2623189	+	993	WP_002367501.1	biotin--[acetyl-CoA-carboxylase] ligase	-
CG806_RS14240	2623453..2624091	-	639	WP_002378863.1	lytic polysaccharide monooxygenase	-
CG806_RS14250	2624777..2626393	+	1617	WP_002372620.1	phosphatase PAP2/LCP family protein	-
CG806_RS14260	2626902..2627090	+	189	WP_002367503.1	putative holin-like toxin	Toxin
-	2627046..2627280	-	235	NuclAT_7	-	Antitoxin
-	2627064..2627282	-	219	NuclAT_11	-	-
CG806_RS14270	2627282..2629903	-	2622	WP_100908296.1	WxL domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (32-62)

Sequences

Toxin

Protein

• Length: 63 a.a.
• Molecular weight: 7259.75 Da
• Isoelectric Point: 10.6710

>T79143 WP_002367503.1 NZ_CP022488:2626902-2627090 [Enterococcus faecalis ARO1/DG]
MCREVMAVAIQSEREVMRMHVFPKFRERRGLLSAYETIQTILGFGMFTIALIVKLLKNDNKK

Nucleotide

• Length: 189 bp

>T79143 NZ_CP022488:2626902-2627090 [Enterococcus faecalis ARO1/DG]
ATGTGTAGAGAAGTTATGGCGGTGGCTATCCAATCTGAAAGAGAGGTGATGCGTATGCACGTATTTCCGAAATTTAGAGA
AAGGAGAGGCCTTTTGTCAGCATATGAAACAATTCAGACGATCCTAGGGTTTGGTATGTTTACCATTGCACTGATTGTGA
AATTGCTTAAAAATGACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 235 bp

>AT79143 NZ_CP022488:c2627280-2627046 [Enterococcus faecalis ARO1/DG]
ATAAAGATGCCCGAGCCTTGAAATAGGAGGATCGGGCATCTTTTGTTGATGGTCTTTTGAGGGTCGTTGTGCTATAATGG
TAATGAAAAGAGAGATATGCTGTAACATACCTCTCTAGTGTAGAGCTGTTTAAGACGATAGCGATTTTTAGTGATTTATA
AAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTCATTTTTAAGCAATTTCACAATCAGTGCAAT

Structures

Antitoxin