Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 5489890..5490545 Replicon chromosome
Accession NZ_CP022411
Organism Pseudomonas sp. RU47

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag CCX46_RS24970 Protein ID WP_127929688.1
Coordinates 5490201..5490545 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag CCX46_RS24965 Protein ID WP_127929687.1
Coordinates 5489890..5490204 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCX46_RS24940 5485435..5486607 - 1173 WP_127929683.1 aspartate aminotransferase family protein -
CCX46_RS24945 5486710..5487615 + 906 WP_127929684.1 LysR family transcriptional regulator -
CCX46_RS24950 5487670..5488074 + 405 WP_127929685.1 GNAT family N-acetyltransferase -
CCX46_RS24955 5488208..5488909 + 702 WP_095048382.1 hypothetical protein -
CCX46_RS24960 5489198..5489689 - 492 WP_127929686.1 RidA family protein -
CCX46_RS24965 5489890..5490204 - 315 WP_127929687.1 helix-turn-helix domain-containing protein Antitoxin
CCX46_RS24970 5490201..5490545 - 345 WP_127929688.1 toxin Toxin
CCX46_RS24975 5490661..5491548 - 888 WP_053123579.1 heme o synthase -
CCX46_RS24980 5491559..5491894 - 336 WP_127929689.1 cytochrome o ubiquinol oxidase subunit IV -
CCX46_RS24985 5491894..5492517 - 624 WP_003227982.1 cytochrome o ubiquinol oxidase subunit III -
CCX46_RS24990 5492521..5494551 - 2031 WP_007916945.1 cytochrome o ubiquinol oxidase subunit I -
CCX46_RS24995 5494555..5495496 - 942 WP_007916947.1 ubiquinol oxidase subunit II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-94)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13341.23 Da        Isoelectric Point: 9.6212

>T79000 WP_127929688.1 NZ_CP022411:c5490545-5490201 [Pseudomonas sp. RU47]
MRTVFFETTIFTTSVGQYLTDDEYRELQAYMQGNPLAGDVMPRTGGFRKLRWADARRGKGRRGGLRVIYYWLMNDGQFWM
FAIYDKDELENLTAEQEKALKKAIDKELKTRGTP

Download         Length: 345 bp

>T79000 NZ_CP022411:c5490545-5490201 [Pseudomonas sp. RU47]
ATGCGAACCGTATTCTTTGAAACAACGATATTTACCACAAGCGTTGGTCAGTACCTGACAGACGATGAGTACCGAGAACT
GCAGGCTTATATGCAGGGCAATCCGTTGGCAGGCGATGTGATGCCCCGAACGGGTGGATTCAGAAAACTACGTTGGGCTG
ATGCTCGACGTGGCAAGGGCCGACGAGGCGGCTTGCGGGTCATCTATTATTGGCTTATGAATGATGGTCAGTTCTGGATG
TTTGCAATTTACGACAAGGATGAGCTTGAGAATCTGACTGCCGAGCAAGAAAAGGCGCTCAAAAAAGCCATAGATAAAGA
GTTGAAAACACGAGGTACCCCATGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11813.79 Da        Isoelectric Point: 10.2425

>AT79000 WP_127929687.1 NZ_CP022411:c5490204-5489890 [Pseudomonas sp. RU47]
MKKRDLFAELMQGVDEMAAQREGKITLRNTVLEDKPVPEVGAQEIVALREKLHMSQAVFAKRIRASPSTLRNWEQEKSKP
NAQAALLIRLVEKFPDMVDRLSAV

Download         Length: 315 bp

>AT79000 NZ_CP022411:c5490204-5489890 [Pseudomonas sp. RU47]
ATGAAAAAACGCGACCTGTTTGCAGAGTTGATGCAGGGCGTTGATGAGATGGCGGCTCAACGCGAAGGAAAAATTACCCT
GCGCAATACAGTGCTTGAGGACAAACCAGTCCCGGAAGTCGGAGCCCAAGAAATCGTGGCTTTGAGAGAAAAGTTACATA
TGTCTCAAGCCGTCTTTGCCAAGCGAATCAGGGCGAGTCCCAGCACTCTGAGAAACTGGGAGCAGGAAAAGTCAAAGCCA
AATGCTCAAGCTGCTTTGTTGATCCGTTTGGTTGAAAAATTCCCTGACATGGTTGACCGCCTGAGCGCCGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References