Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2152246..2152444 Replicon chromosome
Accession NZ_CP022291
Organism Staphylococcus aureus strain EDCC5464

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag CFN13_RS10990 Protein ID WP_075583739.1
Coordinates 2152340..2152444 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2152246..2152284 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFN13_RS10970 2148349..2149014 - 666 WP_001024097.1 SDR family oxidoreductase -
CFN13_RS10975 2149166..2149486 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CFN13_RS10980 2149488..2150468 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
CFN13_RS10985 2150734..2151825 + 1092 WP_000495680.1 hypothetical protein -
- 2152246..2152284 + 39 - - Antitoxin
CFN13_RS10990 2152340..2152444 - 105 WP_075583739.1 hypothetical protein Toxin
CFN13_RS10995 2152542..2152703 - 162 Protein_2038 helix-turn-helix domain-containing protein -
CFN13_RS11005 2153121..2153279 + 159 WP_024928151.1 hypothetical protein -
CFN13_RS11015 2153939..2154796 - 858 WP_000370944.1 Cof-type HAD-IIB family hydrolase -
CFN13_RS11020 2154864..2155646 - 783 WP_000908181.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3861.73 Da        Isoelectric Point: 7.0039

>T78850 WP_075583739.1 NZ_CP022291:c2152444-2152340 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK

Download         Length: 105 bp

>T78850 NZ_CP022291:c2152444-2152340 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTAATCAAGGCCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT78850 NZ_CP022291:2152246-2152284 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References