Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1906488..1906670 Replicon chromosome
Accession NZ_CP022290
Organism Staphylococcus aureus strain EDCC5458

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CFN12_RS14995 Protein ID WP_001801861.1
Coordinates 1906488..1906583 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1906611..1906670 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFN12_RS09690 1902148..1902774 + 627 WP_000669046.1 hypothetical protein -
CFN12_RS09695 1902815..1903159 + 345 WP_000627551.1 DUF3969 family protein -
CFN12_RS09700 1903257..1903808 + 552 WP_000414205.1 hypothetical protein -
CFN12_RS09705 1904026..1904667 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
CFN12_RS09710 1904781..1904966 - 186 WP_000809857.1 hypothetical protein -
CFN12_RS09715 1904968..1905144 - 177 WP_000375476.1 hypothetical protein -
CFN12_RS09720 1905155..1905538 - 384 WP_000070811.1 hypothetical protein -
CFN12_RS09730 1906142..1906285 - 144 WP_001549059.1 transposase -
CFN12_RS14995 1906488..1906583 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1906611..1906670 - 60 - - Antitoxin
CFN12_RS09740 1906706..1906807 + 102 WP_001791893.1 hypothetical protein -
CFN12_RS09745 1906785..1906961 - 177 Protein_1839 transposase -
CFN12_RS09750 1907155..1907532 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA 1880462..1938017 57555


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T78824 WP_001801861.1 NZ_CP022290:1906488-1906583 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T78824 NZ_CP022290:1906488-1906583 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT78824 NZ_CP022290:c1906670-1906611 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References