78673

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-VapI
Location 7788025..7788633 Replicon chromosome
Accession NZ_CP022222
Organism Bradyrhizobium sp. CCBAU 051011

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag ACH79_RS36790 Protein ID WP_161855293.1
Coordinates 7788349..7788633 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag ACH79_RS36785 Protein ID WP_161855292.1
Coordinates 7788025..7788336 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACH79_RS36770 7784506..7785279 - 774 WP_161855289.1 ATPase -
ACH79_RS36775 7785481..7786665 - 1185 WP_161855290.1 amidohydrolase family protein -
ACH79_RS36780 7786821..7788017 - 1197 WP_161855291.1 RluA family pseudouridine synthase -
ACH79_RS36785 7788025..7788336 - 312 WP_161855292.1 HigA family addiction module antidote protein Antitoxin
ACH79_RS36790 7788349..7788633 - 285 WP_161855293.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ACH79_RS36795 7788813..7789757 + 945 WP_161855294.1 alpha/beta hydrolase -
ACH79_RS36800 7789998..7790375 - 378 WP_161856754.1 tautomerase family protein -
ACH79_RS36805 7790554..7791153 + 600 WP_161855295.1 TetR/AcrR family transcriptional regulator -
ACH79_RS36810 7791203..7791919 - 717 WP_161855296.1 tetratricopeptide repeat protein -
ACH79_RS36815 7791916..7793253 - 1338 WP_161855297.1 replication-associated recombination protein A -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-64)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10632.05 Da        Isoelectric Point: 8.0424

>T78673 WP_161855293.1 NZ_CP022222:c7788633-7788349 [Bradyrhizobium sp. CCBAU 051011]
MIVSYRDKRTARFASGRHVKEFSGFARQAELRLDRLESATSLADLAALPGNRLEALRGDRAGLFSIRINDQWRICFGWPE
GSPGPIEVEIVDYH

Download         Length: 285 bp

>T78673 NZ_CP022222:c7788633-7788349 [Bradyrhizobium sp. CCBAU 051011]
ATGATCGTCAGCTATCGGGACAAGCGCACCGCGCGGTTTGCCTCAGGCCGCCACGTCAAGGAGTTCTCCGGTTTTGCGCG
ACAGGCCGAGTTGCGTCTTGATCGACTGGAATCGGCGACCAGTCTGGCTGATTTGGCGGCGTTGCCTGGCAACCGTCTGG
AAGCACTCAGAGGCGACCGTGCTGGACTGTTTTCGATTCGTATCAACGATCAATGGCGAATTTGCTTCGGTTGGCCGGAA
GGATCACCCGGCCCGATCGAAGTGGAAATTGTCGATTATCACTGA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11548.14 Da        Isoelectric Point: 8.8284

>AT78673 WP_161855292.1 NZ_CP022222:c7788336-7788025 [Bradyrhizobium sp. CCBAU 051011]
MPRSPIHPGEHLAEELQELGITAAELSRQIDVPVNRITGIIHGQRGITADTALRLGHWFGTSPQFWMNLQQLYELRLAEN
EVGKEIAALPRRAGRSTSRQVRS

Download         Length: 312 bp

>AT78673 NZ_CP022222:c7788336-7788025 [Bradyrhizobium sp. CCBAU 051011]
ATGCCTCGCTCCCCCATTCATCCCGGCGAACATCTCGCCGAAGAATTGCAAGAGCTTGGAATCACCGCCGCGGAACTTTC
GCGTCAGATTGACGTGCCGGTAAACCGGATTACGGGTATCATTCACGGCCAGCGCGGTATCACCGCCGACACGGCATTGC
GTCTGGGGCACTGGTTTGGCACCAGCCCGCAATTCTGGATGAATTTGCAGCAGCTCTATGAACTGCGCCTCGCCGAAAAC
GAAGTAGGTAAGGAGATCGCAGCGTTGCCGCGCCGCGCCGGCCGATCGACTTCGCGACAAGTTCGGAGCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References