Detailed information of TA system TA078425

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): TMCS/-
• Location: 2301463..2302032
• Replicon: chromosome
• Accession: NZ_CP022096
• Organism: Staphylococcus pettenkoferi strain FDAARGOS_288

Toxin (Protein)

• Gene name: MW1434
• Uniprot ID: -
• Locus tag: CEP67_RS10855
• Protein ID: WP_088606586.1
• Coordinates: 2301463..2301708 (+)
• Length: 82 a.a.

Antitoxin (RNA)

Gene name	MW1433
Locus tag	-
Coordinates	2301679..2302032 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CEP67_RS10825	2297335..2298372	-	1038	WP_088606581.1	site-specific integrase	-
CEP67_RS10830	2298488..2299090	-	603	WP_088606582.1	hypothetical protein	-
CEP67_RS10840	2299356..2299979	-	624	WP_088606583.1	XRE family transcriptional regulator	-
CEP67_RS10845	2300119..2300358	+	240	WP_088606584.1	helix-turn-helix domain-containing protein	-
CEP67_RS10850	2300391..2301146	+	756	WP_088606585.1	phage regulatory protein/antirepressor Ant	-
CEP67_RS12055	2301161..2301322	+	162	WP_167693687.1	hypothetical protein	-
CEP67_RS10855	2301463..2301708	+	246	WP_088606586.1	DUF2829 domain-containing protein	Toxin
-	2301679..2302032	-	354	-	-	Antitoxin
CEP67_RS10865	2302202..2302513	+	312	WP_088606588.1	DUF771 domain-containing protein	-
CEP67_RS12060	2302527..2302691	+	165	WP_167693688.1	hypothetical protein	-
CEP67_RS10870	2302774..2302998	+	225	WP_088606589.1	DUF2483 family protein	-
CEP67_RS10875	2302991..2303662	+	672	WP_088606590.1	ERF family protein	-
CEP67_RS10880	2303662..2304084	+	423	WP_088606591.1	single-stranded DNA-binding protein	-
CEP67_RS10885	2304095..2304763	+	669	WP_088606592.1	hypothetical protein	-
CEP67_RS10890	2305174..2305425	+	252	Protein_2096	helix-turn-helix domain-containing protein	-
CEP67_RS10895	2305495..2305851	+	357	WP_088606593.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	clpP	2297335..2386503	89168

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Protein of unknown function DUF2829 (2-69)

Sequences

Toxin

Protein

• Length: 82 a.a.
• Molecular weight: 9535.89 Da
• Isoelectric Point: 6.4758

>T78425 WP_088606586.1 NZ_CP022096:2301463-2301708 [Staphylococcus pettenkoferi]
MNIQEATKLATKHLVTMTRQEWKESHQTKILPTNDSFLHCLVSNKDGKHLIKYWQPSADDLMADDWEVISPIRDQELLKQ
F

Nucleotide

• Length: 246 bp

>T78425 NZ_CP022096:2301463-2301708 [Staphylococcus pettenkoferi]
ATGAACATTCAAGAAGCAACGAAGTTAGCGACAAAACATCTTGTAACTATGACAAGACAAGAATGGAAGGAAAGTCATCA
AACGAAGATTTTACCAACAAATGATAGTTTTTTACATTGTCTTGTTTCAAATAAAGATGGAAAACATCTTATTAAATATT
GGCAACCTTCAGCTGATGACTTAATGGCAGATGATTGGGAGGTTATCAGCCCAATCAGAGACCAGGAATTATTGAAGCAA
TTTTAG

Antitoxin

Nucleotide

• Length: 354 bp

>AT78425 NZ_CP022096:c2302032-2301679 [Staphylococcus pettenkoferi]
TATCTGATGAATTCGAAGTACTTACTAAAGATCAACAGTATATTTTGTCAGTACTTTATAAAAATTATTTAGAATGTGTT
AAGTCTGGAATTGTTAAACTAACTTGTAATAATTTTGAAAGTGCGGAAGATATACACTCTAAATATTTCCAAAAACTACA
TTTTGAGGATGTAGAAAATGATTTGAAAAAACTTAAAAAGTCTGGATTCCTGAATGGTATTTTTGCAGATAACACCCTTT
ATCATGTGACTATTTCAGATAAAACTATTGTTTATTTCGAAAATGAGTTTAAAAATAATTTGAAAAGTATAATTGATAGC
ATTTCTAAAATTGCTTCAATAATTCCTGGTCTCT

Structures

Antitoxin