Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1553109..1553266 Replicon chromosome
Accession NZ_CP022093
Organism Staphylococcus saprophyticus strain FDAARGOS_355

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CEQ33_RS13010 Protein ID WP_002441941.1
Coordinates 1553171..1553266 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1553109..1553142 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEQ33_RS08110 1548897..1549730 + 834 WP_011304020.1 aldo/keto reductase -
CEQ33_RS08115 1550197..1550496 - 300 WP_011304021.1 hypothetical protein -
CEQ33_RS08120 1550873..1551106 + 234 WP_011304022.1 ferrous iron transport protein A -
CEQ33_RS13005 1551167..1551232 - 66 WP_162009580.1 type I toxin-antitoxin system Fst family toxin -
CEQ33_RS08125 1551420..1552820 - 1401 WP_011304023.1 RES family NAD+ phosphorylase -
- 1553109..1553142 + 34 - - Antitoxin
CEQ33_RS13010 1553171..1553266 - 96 WP_002441941.1 type I toxin-antitoxin system Fst family toxin Toxin
CEQ33_RS08130 1553569..1554327 - 759 WP_011304024.1 MerR family transcriptional regulator -
CEQ33_RS08135 1554437..1555000 - 564 WP_011304025.1 helix-turn-helix domain-containing protein -
CEQ33_RS08140 1555194..1556651 - 1458 WP_011304026.1 carbon starvation protein A -
CEQ33_RS08145 1556859..1557698 - 840 WP_002481957.1 ParB/RepB/Spo0J family partition protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3560.34 Da        Isoelectric Point: 9.9256

>T78413 WP_002441941.1 NZ_CP022093:c1553266-1553171 [Staphylococcus saprophyticus]
MLMIFVHIIAPVISGCAVAYFTYWLSSKRNK

Download         Length: 96 bp

>T78413 NZ_CP022093:c1553266-1553171 [Staphylococcus saprophyticus]
ATGCTTATGATCTTCGTTCACATCATTGCACCAGTCATTAGTGGCTGTGCAGTTGCGTATTTTACTTATTGGCTTAGTAG
TAAACGCAATAAATAG

Antitoxin


Download         Length: 34 bp

>AT78413 NZ_CP022093:1553109-1553142 [Staphylococcus saprophyticus]
CACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References