Detailed information of TA system TA078409

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 2943..3091
• Replicon: plasmid unnamed2
• Accession: NZ_CP022092
• Organism: Staphylococcus saprophyticus strain FDAARGOS_355

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: CEQ33_RS12985
• Protein ID: WP_011276848.1
• Coordinates: 2943..3038 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	3056..3091 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CEQ33_RS13045	332..469	+	138	WP_021459086.1	hypothetical protein	-
CEQ33_RS13050	543..710	-	168	WP_162837505.1	hypothetical protein	-
CEQ33_RS00240	741..971	-	231	WP_031884148.1	SHOCT domain-containing protein	-
CEQ33_RS13055	1105..1305	-	201	WP_073346352.1	hypothetical protein	-
CEQ33_RS00250	1794..2411	+	618	WP_002467537.1	CadD family cadmium resistance transporter	-
CEQ33_RS00255	2430..2777	+	348	WP_002467551.1	metalloregulator ArsR/SmtB family transcription factor	-
CEQ33_RS12985	2943..3038	+	96	WP_011276848.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	3056..3091	+	36	NuclAT_0	-	Antitoxin
CEQ33_RS00260	3393..3866	+	474	WP_077460978.1	thymidylate synthase	-
CEQ33_RS00265	3980..4408	+	429	WP_031885498.1	Rrf2 family transcriptional regulator	-
CEQ33_RS00270	4529..5104	+	576	Protein_10	DsbA family protein	-
CEQ33_RS00275	5121..5771	+	651	WP_031885497.1	NAD(P)-dependent oxidoreductase	-
CEQ33_RS00280	6070..6825	-	756	WP_031863945.1	sulfite exporter TauE/SafE family protein	-
CEQ33_RS00285	6825..7085	-	261	WP_031863946.1	persulfide-sensing transcriptional repressor CstR	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..38554	38554

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3623.38 Da
• Isoelectric Point: 9.5124

>T78409 WP_011276848.1 NZ_CP022092:2943-3038 [Staphylococcus saprophyticus]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Nucleotide

• Length: 96 bp

>T78409 NZ_CP022092:2943-3038 [Staphylococcus saprophyticus]
ATGTTGGAAATCCTTGTTCACATCACGACCACAGTCATCAGTGGTTGTATTATTGCGTTATTTACGCATTGGCTGCGTAA
TCGCAAAGACAAATAG

Antitoxin

Nucleotide

• Length: 36 bp

>AT78409 NZ_CP022092:3056-3091 [Staphylococcus saprophyticus]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin