Detailed information of TA system TA078324

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-RNAII/-
• Location: 687480..687740
• Replicon: chromosome
• Accession: NZ_CP022059
• Organism: Enterococcus faecalis strain FDAARGOS_338

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: CEQ16_RS03650
• Protein ID: WP_002392818.1
• Coordinates: 687597..687740 (-)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	687480..687623 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CEQ16_RS03640	686965..687108	-	144	WP_002381035.1	putative holin-like toxin	-
CEQ16_RS03645	687338..687478	-	141	WP_073340360.1	putative holin-like toxin	-
-	687480..687623	+	144	-	-	Antitoxin
CEQ16_RS03650	687597..687740	-	144	WP_002392818.1	putative holin-like toxin	Toxin
CEQ16_RS03655	688070..689686	-	1617	WP_105577398.1	phosphatase PAP2/LCP family protein	-
CEQ16_RS03665	690379..691008	+	630	WP_002354763.1	lytic polysaccharide monooxygenase	-
CEQ16_RS03670	691272..692264	-	993	WP_002354765.1	biotin--[acetyl-CoA-carboxylase] ligase	-
CEQ16_RS03675	692403..692618	+	216	WP_002354768.1	zinc ribbon domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5344.49 Da
• Isoelectric Point: 10.6323

>T78324 WP_002392818.1 NZ_CP022059:c687740-687597 [Enterococcus faecalis]
MNVSTKIYERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

>T78324 NZ_CP022059:c687740-687597 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCAGCATATGAAACAATTCAGACAATTCTTGGGTTTGG
TATGTTTACCATTGCTTTGATTGCGCTGATTGTGAAATTGCTTAAAAATGACAAGAAAAAATAA

Antitoxin

Nucleotide

• Length: 144 bp

>AT78324 NZ_CP022059:687480-687623 [Enterococcus faecalis]
TGCTACAATAGAGACGAAAAGAGAGGTATGCTCTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCTTTTTA
GTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAA

Structures

Antitoxin