Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | HipBST/HipA(toxin) |
Location | 580642..581912 | Replicon | chromosome |
Accession | NZ_CP022041 | ||
Organism | Prevotella melaninogenica strain FDAARGOS_306 |
Toxin (Protein)
Gene name | HipT | Uniprot ID | - |
Locus tag | CEP85_RS09485 | Protein ID | WP_013265740.1 |
Coordinates | 580642..581577 (-) | Length | 312 a.a. |
Antitoxin (Protein)
Gene name | HipS | Uniprot ID | - |
Locus tag | CEP85_RS09490 | Protein ID | WP_013265071.1 |
Coordinates | 581577..581912 (-) | Length | 112 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CEP85_RS09470 | 576141..576659 | + | 519 | WP_013265649.1 | histidine phosphatase family protein | - |
CEP85_RS09475 | 576933..577802 | - | 870 | WP_013265448.1 | hypothetical protein | - |
CEP85_RS12645 | 578581..578742 | + | 162 | WP_167310037.1 | hypothetical protein | - |
CEP85_RS09480 | 578768..580354 | + | 1587 | WP_013265909.1 | fimbrillin family protein | - |
CEP85_RS09485 | 580642..581577 | - | 936 | WP_013265740.1 | HipA domain-containing protein | Toxin |
CEP85_RS09490 | 581577..581912 | - | 336 | WP_013265071.1 | HipA N-terminal domain-containing protein | Antitoxin |
CEP85_RS09495 | 581909..582112 | - | 204 | WP_013265868.1 | helix-turn-helix transcriptional regulator | - |
CEP85_RS09500 | 582802..584397 | + | 1596 | WP_044046165.1 | hypothetical protein | - |
CEP85_RS09505 | 584431..584880 | + | 450 | WP_013265542.1 | lipocalin-like domain-containing protein | - |
CEP85_RS09510 | 585214..586320 | - | 1107 | WP_044046024.1 | undecaprenyl/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 312 a.a. Molecular weight: 35897.58 Da Isoelectric Point: 8.2694
>T78227 WP_013265740.1 NZ_CP022041:c581577-580642 [Prevotella melaninogenica]
MCKCLYCYQKLEEGQKDFHPHCARKFFGTKDVPLLEYKHKDLEELAEQVIRAQTSLTGVQPKLSLNLNKHDGCNRLTIVG
LWGDYIFKPQTEAYSQLPENEDLTMHLAEAAKIKVVPHSLIRLSDGKLGYLTKRIDRTKNGEKIDMEDMCQLTLHPTEYK
YKGSYEQIAKTITQYSSTPKLDLTNYMQLLLFCFITGNNDMHLKNFSLYRPSKDYQLAPAYDLLNTTIANPKDKEELAMP
LSGRKSKLCLDDFLNTAKTIGLEENIVLRLVKGFEKALPKWKLLIESSFLDEDMKKEYNKLIVSRLNRLQG
MCKCLYCYQKLEEGQKDFHPHCARKFFGTKDVPLLEYKHKDLEELAEQVIRAQTSLTGVQPKLSLNLNKHDGCNRLTIVG
LWGDYIFKPQTEAYSQLPENEDLTMHLAEAAKIKVVPHSLIRLSDGKLGYLTKRIDRTKNGEKIDMEDMCQLTLHPTEYK
YKGSYEQIAKTITQYSSTPKLDLTNYMQLLLFCFITGNNDMHLKNFSLYRPSKDYQLAPAYDLLNTTIANPKDKEELAMP
LSGRKSKLCLDDFLNTAKTIGLEENIVLRLVKGFEKALPKWKLLIESSFLDEDMKKEYNKLIVSRLNRLQG
Download Length: 936 bp
>T78227 NZ_CP022041:c581577-580642 [Prevotella melaninogenica]
ATGTGTAAATGTCTGTATTGCTATCAAAAATTGGAAGAGGGTCAGAAAGACTTTCATCCTCATTGTGCTCGCAAGTTCTT
TGGTACAAAAGATGTTCCCTTATTGGAATATAAACATAAAGACCTCGAAGAATTAGCCGAACAAGTAATCCGCGCCCAGA
CATCGCTGACAGGAGTTCAGCCTAAATTGTCTCTAAACCTCAATAAACACGATGGTTGTAACCGATTAACCATTGTCGGA
CTTTGGGGGGATTATATCTTTAAACCACAGACAGAGGCTTACTCACAGCTGCCTGAAAATGAGGACTTAACAATGCACCT
TGCAGAAGCTGCAAAGATAAAAGTCGTACCACATAGCTTAATTCGTTTGTCTGATGGGAAGTTGGGGTATCTCACCAAGC
GTATTGATCGTACCAAGAATGGTGAGAAAATAGATATGGAGGATATGTGTCAGTTAACGTTACACCCTACAGAATATAAG
TATAAAGGATCGTACGAGCAGATAGCAAAAACGATAACACAATATAGTAGTACACCCAAACTCGACTTAACCAACTATAT
GCAATTATTGCTTTTCTGCTTTATCACTGGTAACAACGACATGCATCTGAAGAACTTCTCTCTTTATCGTCCTTCAAAAG
ATTATCAATTAGCTCCAGCTTATGACCTTCTCAACACTACGATAGCAAATCCTAAAGACAAAGAGGAATTGGCAATGCCG
CTCTCTGGACGAAAATCGAAGCTGTGTCTTGATGACTTCTTAAACACTGCAAAGACAATAGGCTTAGAAGAAAACATTGT
ATTGCGCCTCGTAAAAGGTTTTGAAAAGGCTCTCCCTAAATGGAAGTTGCTCATAGAGAGTTCATTTCTTGACGAAGATA
TGAAAAAGGAATATAATAAACTTATCGTATCCCGATTGAATCGTTTGCAAGGATAA
ATGTGTAAATGTCTGTATTGCTATCAAAAATTGGAAGAGGGTCAGAAAGACTTTCATCCTCATTGTGCTCGCAAGTTCTT
TGGTACAAAAGATGTTCCCTTATTGGAATATAAACATAAAGACCTCGAAGAATTAGCCGAACAAGTAATCCGCGCCCAGA
CATCGCTGACAGGAGTTCAGCCTAAATTGTCTCTAAACCTCAATAAACACGATGGTTGTAACCGATTAACCATTGTCGGA
CTTTGGGGGGATTATATCTTTAAACCACAGACAGAGGCTTACTCACAGCTGCCTGAAAATGAGGACTTAACAATGCACCT
TGCAGAAGCTGCAAAGATAAAAGTCGTACCACATAGCTTAATTCGTTTGTCTGATGGGAAGTTGGGGTATCTCACCAAGC
GTATTGATCGTACCAAGAATGGTGAGAAAATAGATATGGAGGATATGTGTCAGTTAACGTTACACCCTACAGAATATAAG
TATAAAGGATCGTACGAGCAGATAGCAAAAACGATAACACAATATAGTAGTACACCCAAACTCGACTTAACCAACTATAT
GCAATTATTGCTTTTCTGCTTTATCACTGGTAACAACGACATGCATCTGAAGAACTTCTCTCTTTATCGTCCTTCAAAAG
ATTATCAATTAGCTCCAGCTTATGACCTTCTCAACACTACGATAGCAAATCCTAAAGACAAAGAGGAATTGGCAATGCCG
CTCTCTGGACGAAAATCGAAGCTGTGTCTTGATGACTTCTTAAACACTGCAAAGACAATAGGCTTAGAAGAAAACATTGT
ATTGCGCCTCGTAAAAGGTTTTGAAAAGGCTCTCCCTAAATGGAAGTTGCTCATAGAGAGTTCATTTCTTGACGAAGATA
TGAAAAAGGAATATAATAAACTTATCGTATCCCGATTGAATCGTTTGCAAGGATAA
Antitoxin
Download Length: 112 a.a. Molecular weight: 12583.68 Da Isoelectric Point: 4.3774
>AT78227 WP_013265071.1 NZ_CP022041:c581912-581577 [Prevotella melaninogenica]
MRQAEIYRKRILAGILTEDGGEYRFCYDEKYLVQEDAQPISLTFPLQTEPFVSPVLFPFFDGLIPEGWLLDVALRNTNIS
VLDRMSLLLLCCKECIGAVSIIPRKELGGDV
MRQAEIYRKRILAGILTEDGGEYRFCYDEKYLVQEDAQPISLTFPLQTEPFVSPVLFPFFDGLIPEGWLLDVALRNTNIS
VLDRMSLLLLCCKECIGAVSIIPRKELGGDV
Download Length: 336 bp
>AT78227 NZ_CP022041:c581912-581577 [Prevotella melaninogenica]
ATGAGACAAGCAGAAATATATCGAAAGAGAATTCTCGCTGGTATTCTGACAGAAGATGGTGGCGAATACCGATTCTGTTA
TGACGAGAAGTATCTTGTACAGGAAGATGCCCAACCTATAAGTTTGACATTCCCATTACAGACGGAACCGTTTGTAAGTC
CTGTGTTATTCCCATTTTTTGATGGGCTAATACCCGAAGGATGGTTGCTTGATGTGGCACTTCGCAATACCAACATCAGC
GTTCTTGACCGTATGTCGTTATTACTATTATGCTGTAAGGAGTGTATAGGCGCTGTAAGTATTATTCCACGGAAAGAATT
AGGAGGTGATGTATAA
ATGAGACAAGCAGAAATATATCGAAAGAGAATTCTCGCTGGTATTCTGACAGAAGATGGTGGCGAATACCGATTCTGTTA
TGACGAGAAGTATCTTGTACAGGAAGATGCCCAACCTATAAGTTTGACATTCCCATTACAGACGGAACCGTTTGTAAGTC
CTGTGTTATTCCCATTTTTTGATGGGCTAATACCCGAAGGATGGTTGCTTGATGTGGCACTTCGCAATACCAACATCAGC
GTTCTTGACCGTATGTCGTTATTACTATTATGCTGTAAGGAGTGTATAGGCGCTGTAAGTATTATTCCACGGAAAGAATT
AGGAGGTGATGTATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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