Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | ldrD-rdlD/Ldr(toxin) |
Location | 4553632..4553853 | Replicon | chromosome |
Accession | NZ_CP021935 | ||
Organism | Escherichia coli strain AR_0055 |
Toxin (Protein)
Gene name | ldrD | Uniprot ID | A0A1U9U3P9 |
Locus tag | AM434_RS23575 | Protein ID | WP_001531632.1 |
Coordinates | 4553632..4553739 (-) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | rdlD | ||
Locus tag | - | ||
Coordinates | 4553787..4553853 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
AM434_RS23550 | 4549476..4550558 | + | 1083 | WP_000804726.1 | peptide chain release factor 1 | - |
AM434_RS23555 | 4550558..4551391 | + | 834 | WP_000456450.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
AM434_RS23560 | 4551388..4551780 | + | 393 | WP_000200375.1 | invasion regulator SirB2 | - |
AM434_RS23565 | 4551784..4552593 | + | 810 | WP_001257044.1 | invasion regulator SirB1 | - |
AM434_RS23570 | 4552629..4553483 | + | 855 | WP_000811065.1 | 3-deoxy-8-phosphooctulonate synthase | - |
AM434_RS23575 | 4553632..4553739 | - | 108 | WP_001531632.1 | type I toxin-antitoxin system toxin Ldr family protein | Toxin |
- | 4553787..4553853 | + | 67 | NuclAT_10 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_10 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_10 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_10 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_5 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_5 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_5 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_5 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_6 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_6 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_6 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_6 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_7 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_7 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_7 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_7 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_8 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_8 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_8 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_8 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_9 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_9 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_9 | - | Antitoxin |
- | 4553787..4553853 | + | 67 | NuclAT_9 | - | Antitoxin |
- | 4553789..4553852 | + | 64 | NuclAT_12 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_12 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_12 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_12 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_13 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_13 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_13 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_13 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_14 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_14 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_14 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_14 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_15 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_15 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_15 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_15 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_16 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_16 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_16 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_16 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_17 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_17 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_17 | - | - |
- | 4553789..4553852 | + | 64 | NuclAT_17 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_18 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_18 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_18 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_18 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_19 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_19 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_19 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_19 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_20 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_20 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_20 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_20 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_21 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_21 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_21 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_21 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_22 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_22 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_22 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_22 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_23 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_23 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_23 | - | - |
- | 4553789..4553854 | + | 66 | NuclAT_23 | - | - |
AM434_RS23585 | 4554144..4555244 | - | 1101 | WP_000063608.1 | sodium-potassium/proton antiporter ChaA | - |
AM434_RS23590 | 4555514..4555753 | + | 240 | WP_000120702.1 | putative cation transport regulator ChaB | - |
AM434_RS23595 | 4555902..4556597 | + | 696 | WP_001295621.1 | glutathione-specific gamma-glutamylcyclotransferase | - |
AM434_RS23600 | 4556641..4556994 | - | 354 | WP_001169659.1 | DsrE/F sulfur relay family protein YchN | - |
AM434_RS23605 | 4557179..4558573 | + | 1395 | WP_000086187.1 | inverse autotransporter invasin YchO | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 4040.89 Da Isoelectric Point: 12.5163
>T77907 WP_001531632.1 NZ_CP021935:c4553739-4553632 [Escherichia coli]
MTLAQFAMIFWHNLAAPILAGIITAVIVSWWRNRK
MTLAQFAMIFWHNLAAPILAGIITAVIVSWWRNRK
Download Length: 108 bp
>T77907 NZ_CP021935:c4553739-4553632 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACAACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGTGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACAACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGTGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 67 bp
>AT77907 NZ_CP021935:4553787-4553853 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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