Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2415012..2415335 Replicon chromosome
Accession NZ_CP021911
Organism Bacillus sp. MD-5

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag CDO84_RS12140 Protein ID WP_024122157.1
Coordinates 2415012..2415191 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2415115..2415335 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDO84_RS12130 2414238..2414375 - 138 WP_021480099.1 hypothetical protein -
CDO84_RS12135 2414417..2414866 - 450 WP_024122156.1 phage portal protein -
CDO84_RS12140 2415012..2415191 + 180 WP_024122157.1 type I toxin-antitoxin system toxin TxpA Toxin
- 2415115..2415335 - 221 NuclAT_0 - Antitoxin
- 2415115..2415335 - 221 NuclAT_0 - Antitoxin
- 2415115..2415335 - 221 NuclAT_0 - Antitoxin
- 2415115..2415335 - 221 NuclAT_0 - Antitoxin
CDO84_RS21415 2415571..2415660 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
CDO84_RS12150 2415953..2416396 - 444 WP_003229930.1 phage tail tube protein -
CDO84_RS12155 2416399..2417799 - 1401 WP_040082441.1 phage tail sheath family protein -
CDO84_RS12160 2417800..2417991 - 192 WP_082032961.1 hypothetical protein -
CDO84_RS12165 2417988..2418425 - 438 WP_040082440.1 hypothetical protein -
CDO84_RS12170 2418438..2418941 - 504 WP_040082439.1 HK97 gp10 family phage protein -
CDO84_RS12175 2418938..2419300 - 363 WP_040082438.1 YqbH/XkdH family protein -
CDO84_RS12180 2419297..2419692 - 396 WP_015714318.1 DUF3199 family protein -
CDO84_RS12185 2419697..2420008 - 312 WP_040082437.1 YqbF domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2375277..2444984 69707


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T77867 WP_024122157.1 NZ_CP021911:2415012-2415191 [Bacillus sp. MD-5]
MSTYESLMVMIGFANLIGGIMTWVLSLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

>T77867 NZ_CP021911:2415012-2415191 [Bacillus sp. MD-5]
ATGTCGACCTATGAATCTTTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTACTATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin


Download         Length: 221 bp

>AT77867 NZ_CP021911:c2415335-2415115 [Bacillus sp. MD-5]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACAATACAACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCATAAAATATAAAAGCCAGAGTGTTGCAGCACTCTAGCTTTTAAAGAAACTACCCTTTAATAGGA
GGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References