Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2415012..2415335 | Replicon | chromosome |
Accession | NZ_CP021911 | ||
Organism | Bacillus sp. MD-5 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | - |
Locus tag | CDO84_RS12140 | Protein ID | WP_024122157.1 |
Coordinates | 2415012..2415191 (+) | Length | 60 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2415115..2415335 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CDO84_RS12130 | 2414238..2414375 | - | 138 | WP_021480099.1 | hypothetical protein | - |
CDO84_RS12135 | 2414417..2414866 | - | 450 | WP_024122156.1 | phage portal protein | - |
CDO84_RS12140 | 2415012..2415191 | + | 180 | WP_024122157.1 | type I toxin-antitoxin system toxin TxpA | Toxin |
- | 2415115..2415335 | - | 221 | NuclAT_0 | - | Antitoxin |
- | 2415115..2415335 | - | 221 | NuclAT_0 | - | Antitoxin |
- | 2415115..2415335 | - | 221 | NuclAT_0 | - | Antitoxin |
- | 2415115..2415335 | - | 221 | NuclAT_0 | - | Antitoxin |
CDO84_RS21415 | 2415571..2415660 | + | 90 | WP_075058862.1 | type I toxin-antitoxin system toxin BsrH | - |
CDO84_RS12150 | 2415953..2416396 | - | 444 | WP_003229930.1 | phage tail tube protein | - |
CDO84_RS12155 | 2416399..2417799 | - | 1401 | WP_040082441.1 | phage tail sheath family protein | - |
CDO84_RS12160 | 2417800..2417991 | - | 192 | WP_082032961.1 | hypothetical protein | - |
CDO84_RS12165 | 2417988..2418425 | - | 438 | WP_040082440.1 | hypothetical protein | - |
CDO84_RS12170 | 2418438..2418941 | - | 504 | WP_040082439.1 | HK97 gp10 family phage protein | - |
CDO84_RS12175 | 2418938..2419300 | - | 363 | WP_040082438.1 | YqbH/XkdH family protein | - |
CDO84_RS12180 | 2419297..2419692 | - | 396 | WP_015714318.1 | DUF3199 family protein | - |
CDO84_RS12185 | 2419697..2420008 | - | 312 | WP_040082437.1 | YqbF domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 2375277..2444984 | 69707 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 60 a.a. Molecular weight: 6739.19 Da Isoelectric Point: 8.0370
>T77867 WP_024122157.1 NZ_CP021911:2415012-2415191 [Bacillus sp. MD-5]
MSTYESLMVMIGFANLIGGIMTWVLSLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
MSTYESLMVMIGFANLIGGIMTWVLSLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
Download Length: 180 bp
>T77867 NZ_CP021911:2415012-2415191 [Bacillus sp. MD-5]
ATGTCGACCTATGAATCTTTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTACTATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG
ATGTCGACCTATGAATCTTTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTACTATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG
Antitoxin
Download Length: 221 bp
>AT77867 NZ_CP021911:c2415335-2415115 [Bacillus sp. MD-5]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACAATACAACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCATAAAATATAAAAGCCAGAGTGTTGCAGCACTCTAGCTTTTAAAGAAACTACCCTTTAATAGGA
GGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACAATACAACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCATAAAATATAAAAGCCAGAGTGTTGCAGCACTCTAGCTTTTAAAGAAACTACCCTTTAATAGGA
GGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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