Detailed information of TA system TA077863

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrG-as-bsrH/-
• Location: 1931532..1931825
• Replicon: chromosome
• Accession: NZ_CP021911
• Organism: Bacillus sp. MD-5

Toxin (Protein)

• Gene name: bsrG
• Uniprot ID: -
• Locus tag: CDO84_RS21365
• Protein ID: WP_052438156.1
• Coordinates: 1931532..1931648 (+)
• Length: 39 a.a.

Antitoxin (RNA)

Gene name	as-bsrH
Locus tag	-
Coordinates	1931643..1931825 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CDO84_RS21355	1926840..1926981	+	142	Protein_1797	phage holin	-
CDO84_RS09290	1927135..1928250	+	1116	Protein_1798	response regulator aspartate phosphatase RapK	-
CDO84_RS09295	1928247..1928369	+	123	WP_004399440.1	phosphatase RapK inhibitor PhrK	-
CDO84_RS21565	1928597..1929218	-	622	Protein_1800	DNA repair protein	-
CDO84_RS09310	1929258..1929602	-	345	Protein_1801	UV damage repair protein UvrX	-
CDO84_RS09315	1929650..1929919	-	270	WP_040082935.1	YolD-like family protein	-
CDO84_RS09320	1930093..1930428	+	336	WP_040082934.1	hypothetical protein	-
CDO84_RS09325	1930471..1930827	-	357	WP_040082933.1	hypothetical protein	-
CDO84_RS09330	1930833..1931300	-	468	WP_040082931.1	YolA family protein	-
CDO84_RS21365	1931532..1931648	+	117	WP_052438156.1	type I toxin-antitoxin system toxin BsrG	Toxin
-	1931643..1931825	-	183	NuclAT_1	-	Antitoxin
-	1931643..1931825	-	183	NuclAT_1	-	Antitoxin
-	1931643..1931825	-	183	NuclAT_1	-	Antitoxin
-	1931643..1931825	-	183	NuclAT_1	-	Antitoxin
CDO84_RS09335	1931949..1932407	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
CDO84_RS09340	1932417..1934219	-	1803	WP_040082929.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
CDO84_RS09345	1934428..1935888	+	1461	WP_040082928.1	hypothetical protein	-
CDO84_RS09350	1935910..1936023	+	114	Protein_1810	excalibur calcium-binding domain-containing protein	-
CDO84_RS09355	1936147..1936680	-	534	WP_040082927.1	N-acetyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1906825..1937605	30780

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-38)

Sequences

Toxin

Protein

• Length: 39 a.a.
• Molecular weight: 4322.37 Da
• Isoelectric Point: 10.1022

>T77863 WP_052438156.1 NZ_CP021911:1931532-1931648 [Bacillus sp. MD-5]
MTVYESLMVMINFGGLILNTVLLIFNIMMIVTSSQKKK

Nucleotide

• Length: 117 bp

>T77863 NZ_CP021911:1931532-1931648 [Bacillus sp. MD-5]
ATGACTGTTTACGAATCATTAATGGTAATGATCAATTTTGGCGGGTTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCGAGCCAAAAGAAAAAATAG

Antitoxin

Nucleotide

• Length: 183 bp

>AT77863 NZ_CP021911:c1931825-1931643 [Bacillus sp. MD-5]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATGAAATGCATAAAATAAAAAAGGTCAGGGTGCTACCAACA
CCCCGACTCTGTACAAAAAGCTGCCCATCAAAGGGCTTGCTCAAATGCATGTGACATAGTAGATCAACCCCTTAGGGTCG
CAATCTCAAGGGGAGGTCTATTT

Structures

Antitoxin